Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.50 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.50 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.46 |
| ▸ | CASP5 | P51878 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856538 | 0.87 | GAA (0.58) | HPGDPOLBGAAMEN1KMT2A | |
| SCHEMBL11194501 | 0.87 | LMNA (0.51) | TNKSPARP1PARP10TNKS2PARP2 | |
| SCHEMBL11197047 | 0.84 | KDM4E (0.52) | GAAMAPK1KDM4E | |
| SCHEMBL11196110 | 0.84 | ALDH1A1 (0.50) | POLBGAAMEN1KMT2ATSHR | |
| SCHEMBL11201299 | 0.81 | USP2 (0.50) | GAACYP2D6CYP3A4MEN1CYP2C9 | |
| SCHEMBL10860653 | 0.81 | SIGMAR1 (0.54) | POLBGAAMEN1KMT2ATSHR | |
| SCHEMBL11197942 | 0.80 | HRH3 (0.45) | GAAMEN1KMT2ATSHRMAPK1 | |
| SCHEMBL11200656 | 0.80 | SIGMAR1 (0.57) | GAATSHRALDH1A1KDM4EHTT | |
| SCHEMBL11206897 | 0.78 | ALDH1A1 (0.54) | MEN1KMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL16826336 | 0.77 | TNKS (0.50) | TNKSPARP1PARP10TNKS2PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4582833-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1986-04-15 | — | — | US | disclosed |