Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.44 |
| ▸ | HTR3B | O95264 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11194501 | 0.89 | LMNA (0.51) | KDM4EMAPK1GAADRD4 | |
| SCHEMBL11196110 | 0.86 | ALDH1A1 (0.50) | MAPTMAPK1GAAL3MBTL1ACHE | |
| SCHEMBL10856538 | 0.86 | GAA (0.58) | KDM4EMAPTMAPK1GAADRD4 | |
| SCHEMBL10851723 | 0.84 | TNKS (0.50) | KDM4EMAPK1GAA | |
| SCHEMBL11201299 | 0.83 | USP2 (0.50) | MAPK1GAAARKCNH2OPRM1 | |
| SCHEMBL10860653 | 0.83 | SIGMAR1 (0.54) | HTR1AHTR2CGAAOPRM1 | |
| SCHEMBL11197942 | 0.82 | HRH3 (0.45) | MAPK1GAA | |
| SCHEMBL11200656 | 0.79 | SIGMAR1 (0.57) | KDM4EMAPTHTR1AGAAL3MBTL1 | |
| SCHEMBL11202780 | 0.78 | POLB (0.56) | KDM4EMAPK1HTR1ADRD4OPRK1 | |
| SCHEMBL16825881 | 0.78 | KDM4E (0.52) | KDM4EMAPTMAPK1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | disclosed |