SCHEMBL1120982

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1120944	0.81	CYP1A2 (0.41)	SMN1; SMN2KMT2ACYP1A2CYP3A4HRH1
	SCHEMBL4370206	0.78	MAPT (0.59)	MAPTSMN1; SMN2LIN28ATDP1KCNA5
	SCHEMBL1121246	0.77	HDAC8 (0.39)	SMN1; SMN2CYP1A2CYP3A4NR1H2NR1H3
	SCHEMBL1120955	0.75	MAPT (0.40)	MAPTKCNA5NPSR1ALDH1A1HDAC8
	SCHEMBL1121145	0.72	KMT2A (0.39)	KCNA5KMT2AMEN1TSHRCYP2C19
	SCHEMBL23642768	0.71	MAPT (0.59)	MAPTSMN1; SMN2LIN28ATDP1KCNA5
	SCHEMBL1121025	0.71	APP (0.33)	TSHR
	SCHEMBL230049	0.71	MAPT (0.64)	MAPTSMN1; SMN2LIN28ATDP1KCNA5
	SCHEMBL1121070	0.70	RXRA (0.38)	—
	SCHEMBL138261	0.69	SMN1; SMN2 (0.83)	MAPTSMN1; SMN2LIN28ATDP1KCNA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.