SCHEMBL1121010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10957338	0.77	CHRNB2 (0.40)	CHRNB2CHRNA4MEN1KMT2ACYP1A2
	SCHEMBL4558460	0.75	CHRNB2 (0.58)	CHRNB2CHRNA4KMT2ACYP1A2CYP2D6
	SCHEMBL29899120	0.75	CHRNB2 (0.58)	CHRNB2CHRNA4KMT2ACYP1A2CYP2D6
	SCHEMBL1120979	0.74	LMNA (0.51)	MEN1KMT2ACYP1A2CYP2D6ALDH1A1
	SCHEMBL6739402	0.71	GRM2 (0.74)	CHRNB2CHRNA4CYP3A4GRM2
	SCHEMBL6171116	0.71	CYP3A4 (0.46)	KMT2ACYP1A2CYP2D6CYP3A4CYP2C9
	SCHEMBL12888668	0.70	CHRNB2 (0.67)	CHRNB2CHRNA4CYP1A2CYP2D6KDM4E
	SCHEMBL1773262	0.70	TBXAS1 (0.56)	MEN1KMT2ACYP1A2CYP2D6CHRNA7
	SCHEMBL6227025	0.69	CHRNB2 (0.64)	CHRNB2CHRNA4CYP1A2CYP2D6CYP3A4
	SCHEMBL1121064	0.69	SLC6A3 (0.41)	KMT2ANR1H3NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.