Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 known ✓ | P09917 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241505 | 0.90 | GCGR (0.38) | TTRGCGRALDH1A1TRPV1KDM4E | |
| SCHEMBL11257903 | 0.90 | GCGR (0.38) | TTRGCGRALDH1A1TRPV1KDM4E | |
| SCHEMBL546994 | 0.84 | DCTPP1 (0.40) | GCGRALDH1A1TRPV1KDM4EHPGD | |
| SCHEMBL11249133 | 0.76 | ELANE (0.40) | ALDH1A1TRPV1CNR2 | |
| SCHEMBL546995 | 0.76 | DCTPP1 (0.40) | GCGRALDH1A1TRPV1KDM4EHPGD | |
| SCHEMBL8417678 | 0.75 | TRPV1 (0.41) | ALDH1A1TRPV1CNR2ALOX5 | |
| SCHEMBL5589592 | 0.75 | GCGR (0.46) | GCGRALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11787239 | 0.75 | KDM4E (0.38) | ALDH1A1KDM4EHPGDHSD17B10CNR2 | |
| Sulfuric Acid SCHEMBL11848808 | 0.74 | ELANE (0.42) | GCGRTRPV1DCTPP1CNR2SLC37A4 | |
| SCHEMBL18140249 | 0.72 | KDM4E (0.38) | ALDH1A1KDM4EHPGDHSD17B10CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4321079-A | Aqueous sulfur dispersion having reduced corrosive activity toward ferrous metal | STANDARD OIL COMPANY (INDIANA) (US) | 1982-03-23 | — | — | US | disclosed |
| US-4316070-A | Cookware with liquid microwave energy moderator | PROSISE ROBERT L | 1982-02-16 | — | — | US | disclosed |
| US-4256691-A | ZINC OR MAGNESIUM COMPOUNDS IN AMMONIA | STANDARD OIL COMPANY (INDIANA) (US) | 1981-03-17 | — | — | US | disclosed |