SCHEMBL11242567

SCHEMBL11242567

Cc1noc(Cl)c1OC(=O)O

nearest known ligand 0.34

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.34
NPC1 O15118 2/20 0.34
POLB P06746 2/20 0.33
ALDH1A1 P00352 4/20 0.32
HPGD P15428 1/20 0.32
TSHR P16473 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
P2RX7 Q99572 3/20 0.31
HTT P42858 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALOX15 P16050 1/20 0.31
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
RAB9A P51151 2/20 0.31
USP2 O75604 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ATM Q13315 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3417324 0.80 GAA (0.37) L3MBTL1ALDH1A1TSHRMEN1KMT2A
SCHEMBL7030589 0.74 ALDH1A1 (0.33) L3MBTL1ALDH1A1
SCHEMBL9199703 0.74 POLB (0.37) L3MBTL1NPC1POLBMEN1KMT2A
SCHEMBL27440736 0.71
SCHEMBL8305745 0.69 ALDH1A1 (0.39) L3MBTL1POLBALDH1A1HPGDTSHR
SCHEMBL9526741 0.69 LMNA (0.43) L3MBTL1ALDH1A1HPGDMEN1KMT2A
SCHEMBL4970350 0.69 HCAR2 (0.36) ALDH1A1HPGDTSHRP2RX7
SCHEMBL9527355 0.68 POLB (0.34) L3MBTL1NPC1POLBALDH1A1HPGD
SCHEMBL9526216 0.68 ALDH1A1 (0.37) L3MBTL1NPC1POLBALDH1A1HTT
SCHEMBL9205871 0.66 HPGD (0.40) L3MBTL1NPC1POLBALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0026873-B1 ISOXAZOLECARBOXYLIC ACID ANILIDES, THEIR PREPARATION, FUNGICIDAL COMPOSITIONS AND PROCESS FOR COMBATING FUNGI BASF Aktiengesellschaft (DE) 1982-10-06 EP disclosed
EP-0026873-A1 Isoxazolecarboxylic acid anilides, their preparation, fungicidal compositions and process for combating fungi BASF Aktiengesellschaft (DE) 1981-04-15 EP disclosed