Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9524891 | 0.85 | TSHR (0.37) | POLBALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL9446176 | 0.78 | POLB (0.37) | POLBALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL9199703 | 0.76 | POLB (0.37) | POLBRAB9ANPC1MEN1KMT2A | |
| SCHEMBL3417324 | 0.71 | GAA (0.37) | ALDH1A1TP53TSHRMEN1KMT2A | |
| SCHEMBL9526741 | 0.71 | LMNA (0.43) | ALDH1A1HPGDSMN1; SMN2MAPTMEN1 | |
| SCHEMBL9526216 | 0.70 | ALDH1A1 (0.37) | POLBALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11242567 | 0.68 | L3MBTL1 (0.34) | POLBALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL27583225 | 0.68 | GAA (0.44) | ALDH1A1ALOX15HSD17B10TP53TSHR | |
| SCHEMBL9205871 | 0.68 | HPGD (0.40) | POLBALDH1A1RAB9AHPGDNPC1 | |
| SCHEMBL7030589 | 0.66 | ALDH1A1 (0.33) | ALDH1A1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337263-B1 | ISOXAZOL(ISOTHIAZOLS)-5-CARBOXAMIDES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0337263-A2 | Isoxazol(isothiazols)-5-carboxamides | BASF Aktiengesellschaft (DE) | 1989-10-18 | — | — | EP | disclosed |