Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | CCR8 | P51685 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255005 | 0.89 | SCN1A (0.41) | SCN1ASCN2ASCN3ARECQLOPRM1 | |
| SCHEMBL11246081 | 0.83 | MMP1 (0.45) | MMP1MMP9MMP13ADAM17SCN1A | |
| SCHEMBL11243000 | 0.80 | USP2 (0.43) | MMP9CCR8KCNH2KMT2AMAPT | |
| SCHEMBL11258118 | 0.78 | SLC6A9 (0.43) | OPRM1SLC6A4MAPTALDH1A1LMNA | |
| SCHEMBL11241295 | 0.78 | USP2 (0.40) | MMP9SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL7510098 | 0.75 | MMP9 (0.54) | MMP1MMP9MMP13ADAM17SCN1A | |
| SCHEMBL11245572 | 0.75 | OPRM1 (0.56) | MMP1MMP9MMP13ADAM17OPRM1 | |
| SCHEMBL11248097 | 0.74 | SLC6A2 (0.41) | KCNH2OPRM1SIGMAR1SLC6A2SLC6A4 | |
| Bromide SCHEMBL11249246 | 0.73 | SLC6A2 (0.40) | KCNH2OPRM1SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL11468367 | 0.73 | SCN1A (0.48) | SCN1ASCN2ASCN3AKCNH2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0016261-B1 | SPIRO(DIBENZ(B,F)OXEPIN-PIPERIDINES) AND METHODS OF PREPARING SAME | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-12-29 | — | — | EP | disclosed |
| EP-0016261-A1 | Spiro(dibenz(b,f)oxepin-piperidines) and methods of preparing same | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-10-01 | — | — | EP | disclosed |