Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1682378 | 0.98 | ALDH1A1 (0.61) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL1187335 | 0.82 | ALDH1A1 (0.57) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL863328 | 0.81 | NR4A1 (0.61) | ALDH1A1CYP3A4MEN1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL14157190 | 0.80 | ALDH1A1 (0.61) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL1337887 | 0.79 | MAOB (0.55) | ALDH1A1CYP3A4KMT2AKDM4ECYP1A2 | |
| SCHEMBL254529 | 0.78 | CA12 (0.50) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL29513208 | 0.78 | CA12 (0.50) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL234263 | 0.78 | ALDH1A1 (0.64) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL29387850 | 0.78 | ALDH1A1 (0.64) | ALDH1A1CYP3A4MEN1MAPTTHRB | |
| SCHEMBL1000566 | 0.78 | ALDH1A1 (0.42) | ALDH1A1CYP3A4MEN1KMT2ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 786 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12344571-B1 | Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2025-07-01 | — | — | US | claimed |
| CN-118184650-A | 6- (1H-pyrrolo [2,3-b ] pyridin-3-yl) quinazoline-4-amine derivative, and preparation method and application thereof | 中国人民解放军北部战区总医院 | 2024-06-14 | — | — | CN | claimed |
| CN-117586206-A | Pterocarpus stilbene piperidine amide derivative, preparation method and medical application thereof | 安徽中医药大学 | 2024-02-23 | — | — | CN | claimed |
| CN-114478474-B | Amide compound and preparation method thereof | 中国科学院宁波材料技术与工程研究所 | 2023-06-30 | — | — | CN | claimed |
| CN-112004813-A | Oxadiazole compounds for controlling phytopathogenic fungi | PI工业有限公司 | 2020-11-27 | — | — | CN | claimed |
| US-10167275-B2 | AZD9291 intermediate and preparation method therefor | SUZHOU MIRACPHARMA TECHNOLOGY CO., LTD. (CN) | 2019-01-01 | — | — | US | claimed |
| US-20180072706-A1 | AZD9291 INTERMEDIATE AND PREPARATION METHOD THEREFOR | SUZHOU MIRACPHARMA TECHNOLOGY CO., LTD. (CN) | 2018-03-15 | — | — | US | claimed |
| EP-2906559-B1 | AZAINDOLINES | HOFFMANN LA ROCHE (CH) | 2017-02-08 | — | — | EP | claimed |
| CN-104311485-B | A kind of preparation method treating leukemic medicine bosutinib | 烟台市华文欣欣医药科技有限公司 | 2016-08-24 | — | — | CN | claimed |
| US-9309248-B2 | Azaindolines | HOFFMANN-LA ROCHE INC. (US) | 2016-04-12 | — | — | US | claimed |
| EP-1831206-B1 | N-SUBSTITUTED BENZIMIDAZOLYL C-KIT INHIBITORS AND COMBINATORIAL BENZIMIDAZOLE LIBRARY | OSI PHARM INC (US) | 2011-08-24 | — | — | EP | claimed |
| CN-101020628-A | Preparation method of 2, 4-difluoro-3-hydroxybenzoic acid | CHEN WEIDONG (CN) | 2007-08-22 | — | — | CN | claimed |
| US-20040110778-A1 | Heterocyclic compounds as ligands of the GABAA receptor | YOHANNES DANIEL (US) | 2004-06-10 | — | — | US | claimed |
| EP-1325006-A2 | HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABA A? RECEPTOR | NEUROGEN CORPORATION (US) | 2003-07-09 | — | — | EP | claimed |
| US-20030105081-A1 | Heterocyclic compounds as ligands of the GABAA receptor | PFIZER INC | 2003-06-05 | — | — | US | claimed |
| EP-1030838-B1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | PFIZER PROD INC (US) | 2003-01-22 | — | — | EP | claimed |
| WO-2002012442-A2 | HETEROCYCLIC COMPOUNDS AS LIGANDS OF THE GABAA RECEPTOR | NEUROGEN CORPORATION (US) | 2002-02-14 | — | — | WO | claimed |
| US-6262272-B1 | REACTING FURAN CARBOXYLIC ACID DERIVATIVE WITH ACID CHLORIDE OR ACID ANHYDRIDE IN INERT SOLVENT CONTAINING ACID RECEPTOR; ADDING AROMATIC AMINE COMPOUND TO FORM PYRROLE CARBOXAMIDE COMPOUND | PFIZER INC | 2001-07-17 | — | — | US | claimed |
| EP-1030838-A1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | Pfizer Products Inc. (US) | 2000-08-30 | — | — | EP | claimed |
| WO-1999025684-A1 | METHOD OF SYNTHESIS OF PYRROLE AMIDES | PFIZER PRODUCTS INC. (US) | 1999-05-27 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105081-A1 | Heterocyclic compounds as ligands of the GABAA receptor | GABRB1, GABRP, GABRA1 | ALDH1A1 1197/4885CYP3A4 403/4885MEN1 2641/4885 |
| US-10167275-B2 | AZD9291 intermediate and preparation method therefor | WEE2, WEE1, PIM1 | ALDH1A1 1494/4885CYP3A4 134/4885MEN1 1426/4885 |
| US-20040110778-A1 | Heterocyclic compounds as ligands of the GABAA receptor | GABRB1, GABRP, GABRA1 | ALDH1A1 1197/4885CYP3A4 403/4885MEN1 2641/4885 |
| US-20180072706-A1 | AZD9291 INTERMEDIATE AND PREPARATION METHOD THEREFOR | WEE2, WEE1, PIM1 | ALDH1A1 1494/4885CYP3A4 134/4885MEN1 1426/4885 |
| US-12344571-B1 | Organic color center-tailored, semiconducting carbon nanotubes and their method of manufacture | NOS1, NOS3, NOS2 | ALDH1A1 754/4885CYP3A4 1460/4885MEN1 4081/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.