Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | LIMK2 | P53671 | 4/20 | 0.55 |
| ▸ | LIMK1 | P53667 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | AGER | Q15109 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11320468 | 0.82 | AGER (0.50) | LIMK2LIMK1AGERHDAC1HDAC6 | |
| SCHEMBL11224728 | 0.81 | TMEM97 (0.49) | MAPTLIMK2LIMK1AGERHDAC1 | |
| SCHEMBL22591141 | 0.78 | LPAR1 (0.56) | ALDH1A1LIMK2LIMK1AGERHDAC1 | |
| SCHEMBL11329956 | 0.76 | MEN1 (0.48) | NPC1L3MBTL1MAPTPOLBAGER | |
| SCHEMBL10888540 | 0.75 | ALDH1A1 (0.51) | ALDH1A1NPC1L3MBTL1MAPTLIMK2 | |
| SCHEMBL11496730 | 0.75 | ALDH1A1 (0.43) | ALDH1A1NPC1L3MBTL1MAPTLIMK2 | |
| SCHEMBL9132014 | 0.75 | HDAC1 (0.63) | ALDH1A1LIMK2LIMK1HDAC1HDAC6 | |
| SCHEMBL3126416 | 0.74 | LPAR1 (0.57) | POLBMEN1KMT2A | |
| SCHEMBL11496728 | 0.74 | ALDH1A1 (0.46) | ALDH1A1NPC1L3MBTL1MAPTPOLB | |
| SCHEMBL11320955 | 0.73 | OPRD1 (0.44) | LIMK2LIMK1AGERHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002836-B1 | ACYLHYDROCARBYLAMINOALCANECARBOXYLIC ACIDS, THEIR PREPARATION AND THEIR USE, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1982-10-27 | — | — | EP | disclosed |
| US-4243678-A | GASTROINTESTINAL DISORDERS, LIVER DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-01-06 | — | — | US | disclosed |
| EP-0002836-A1 | Acylhydrocarbylaminoalcanecarboxylic acids, their preparation and their use, and pharmaceutical compositions containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1979-07-11 | — | — | EP | disclosed |