SCHEMBL1126664

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127203	0.86	NPY2R (0.44)	NPY2RSLC1A2CCR3GAAMAPT
	SCHEMBL1127163	0.84	MAPT (0.41)	NPY2RGAAMAPTALDH1A1POLB
	SCHEMBL1126843	0.83	SLC1A2 (0.41)	NPY2RSLC1A2CCR3HTR1AHTR1D
	SCHEMBL1127152	0.83	NAMPT (0.53)	SLC1A2MAPTALDH1A1POLBNPC1
	SCHEMBL1126696	0.82	MAPT (0.50)	GAAMAPTALDH1A1POLBNPC1
	SCHEMBL1126487	0.81	MAPT (0.51)	GAAMAPTALDH1A1POLBHSD17B10
	SCHEMBL1127109	0.81	MAPT (0.52)	GAAMAPTALDH1A1HSD17B10NPC1
	SCHEMBL1126909	0.79	MEN1 (0.41)	NPY2RGAAMAPTALDH1A1POLB
	SCHEMBL1992485	0.78	ALDH1A1 (0.48)	HTR1AHTR2AHTR2CGAAMAPT
	SCHEMBL19661313	0.78	GAA (0.42)	GAAMAPTALDH1A1POLBHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.