Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126693 | 0.82 | MEN1 (0.49) | MEN1KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL1126783 | 0.79 | RAB9A (0.42) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL1126781 | 0.71 | TSHR (0.38) | RAB9AMEN1KMT2AHPGDTSHR | |
| SCHEMBL1126737 | 0.70 | BRD4 (0.38) | KMT2ATACR1MAPTKDM4EFABP4 | |
| SCHEMBL1081579 | 0.70 | GRIA4 (0.47) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL1126595 | 0.68 | RAB9A (0.48) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL1127139 | 0.68 | MAPT (0.48) | RAB9ANPC1MEN1KMT2ATP53 | |
| SCHEMBL1127158 | 0.67 | FAAH (0.42) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL1127303 | 0.66 | CHRNB2 (0.50) | RAB9ANPC1MEN1KMT2AHPGD | |
| SCHEMBL3190678 | 0.65 | RXFP1 (0.54) | RAB9ANPC1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |