SCHEMBL1126783

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127303	0.87	CHRNB2 (0.50)	RAB9AMEN1KMT2ANPC1MAPT
	SCHEMBL1127233	0.82	MEN1 (0.50)	MEN1KMT2AHTTMAPTLMNA
	SCHEMBL1989265	0.81	MAPK1 (0.46)	MEN1KMT2AHTTTSHRSMN1; SMN2
	SCHEMBL1126824	0.79	RAB9A (0.43)	RAB9AMEN1KMT2ANPC1TP53
	SCHEMBL1126720	0.79	TNF (0.44)	RAB9AMEN1KMT2ANPC1HTT
	SCHEMBL1126896	0.76	RAB9A (0.49)	RAB9AMEN1KMT2ANPC1TP53
	SCHEMBL1126750	0.75	GAA (0.37)	RAB9ANPC1TP53MAPTSMN1; SMN2
	SCHEMBL1989252	0.74	MTNR1B (0.40)	KMT2ATP53HTTMAPTLMNA
	SCHEMBL1992161	0.74	MAPT (0.44)	RAB9AMEN1KMT2AHTTMAPT
	SCHEMBL1126798	0.74	AR (0.39)	MEN1KMT2AHTTMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.