SCHEMBL1127303

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126720	0.88	TNF (0.44)	CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
	SCHEMBL1126783	0.87	RAB9A (0.42)	CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
	SCHEMBL1127233	0.85	MEN1 (0.50)	ALDH1A1LMNAMEN1KMT2AKDM4E
	SCHEMBL1126896	0.83	RAB9A (0.49)	ALDH1A1HPGDLMNANPC1RAB9A
	SCHEMBL1989265	0.82	MAPK1 (0.46)	ALDH1A1MEN1KMT2AKDM4ECYP2C19
	SCHEMBL2229181	0.79	THRB (0.60)	CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
	SCHEMBL1989252	0.77	MTNR1B (0.40)	ALDH1A1LMNAKMT2AMAPTSMN1; SMN2
	SCHEMBL942068	0.76	CHRNB2 (0.45)	CHRNB2CHRNB4CHRNA3CHRNA4ALDH1A1
	SCHEMBL1126812	0.76	ALDH1A1 (0.48)	ALDH1A1HPGDLMNANPC1RAB9A
	SCHEMBL1127545	0.75	RAB9A (0.50)	ALDH1A1LMNANPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.