Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | STAT1 | P42224 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127593 | 0.94 | CSF1R (0.38) | CSF1RALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL1127422 | 0.88 | RAB9A (0.41) | CSF1RALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL1126894 | 0.86 | LMNA (0.48) | ALDH1A1MAPTRAB9ALMNAGAA | |
| SCHEMBL1127408 | 0.83 | RAB9A (0.39) | CSF1RALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL1127778 | 0.83 | LMNA (0.39) | CSF1RALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL1127399 | 0.81 | LMNA (0.35) | CSF1RALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL1126902 | 0.80 | LMNA (0.38) | CSF1RALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL1127186 | 0.79 | MTNR1A (0.45) | ALDH1A1HPGDCYP1A2CYP2C19MAPT | |
| SCHEMBL1126974 | 0.78 | LMNA (0.43) | CSF1RALDH1A1HPGDCYP1A2XBP1 | |
| SCHEMBL1127366 | 0.74 | LMNA (0.37) | CSF1RALDH1A1HPGDCYP1A2XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |