Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 9/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126936 | 0.86 | CSF1R (0.39) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1127778 | 0.83 | LMNA (0.39) | LMNAALDH1A1RAB9AMCL1GAA | |
| SCHEMBL1127399 | 0.81 | LMNA (0.35) | LMNAALDH1A1RAB9AMCL1GAA | |
| SCHEMBL1127186 | 0.79 | MTNR1A (0.45) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1127408 | 0.79 | RAB9A (0.39) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1126974 | 0.78 | LMNA (0.43) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1126902 | 0.78 | LMNA (0.38) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1127366 | 0.74 | LMNA (0.37) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1126655 | 0.74 | TBXAS1 (0.42) | ALDH1A1SMN1; SMN2RAB9AHTTMAPT | |
| SCHEMBL1126648 | 0.69 | CSF1R (0.37) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |