Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127399 | 0.81 | LMNA (0.35) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL1126894 | 0.79 | LMNA (0.48) | ALDH1A1TSHRNPC1LMNARAB9A | |
| SCHEMBL1127778 | 0.79 | LMNA (0.39) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL1126936 | 0.79 | CSF1R (0.39) | CYP1A2CYP3A4CYP2C9HPGDCYP2C19 | |
| SCHEMBL1127408 | 0.74 | RAB9A (0.39) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL1126655 | 0.74 | TBXAS1 (0.42) | KDM4EALDH1A1TDP1RAB9ASMN1; SMN2 | |
| SCHEMBL1126902 | 0.73 | LMNA (0.38) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL1127366 | 0.72 | LMNA (0.37) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 | |
| SCHEMBL1126974 | 0.71 | LMNA (0.43) | CYP1A2HPGDCYP2C19ALDH1A1TDP1 | |
| SCHEMBL1126648 | 0.69 | CSF1R (0.37) | CYP1A2HPGDCYP2C19KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |