Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | STAT1 | P42224 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127376 | 0.82 | LMNA (0.40) | LMNATDP1PIM1MAPTRAB9A | |
| SCHEMBL1127186 | 0.81 | MTNR1A (0.45) | LMNATDP1MAPTRAB9AALDH1A1 | |
| SCHEMBL1126894 | 0.81 | LMNA (0.48) | LMNAMAPTRAB9AMCL1ALDH1A1 | |
| SCHEMBL1126936 | 0.81 | CSF1R (0.39) | LMNATDP1MAPTRAB9ASTAT1 | |
| SCHEMBL1127778 | 0.81 | LMNA (0.39) | LMNATDP1MAPTRAB9ASTAT1 | |
| SCHEMBL1126655 | 0.76 | TBXAS1 (0.42) | TDP1MAPTRAB9ASTAT1NPSR1 | |
| SCHEMBL1127408 | 0.76 | RAB9A (0.39) | LMNATDP1PIM1MAPTRAB9A | |
| SCHEMBL1126902 | 0.75 | LMNA (0.38) | LMNATDP1PIM1MAPTRAB9A | |
| SCHEMBL1127366 | 0.74 | LMNA (0.37) | LMNATDP1PIM1MAPTRAB9A | |
| SCHEMBL1126974 | 0.72 | LMNA (0.43) | LMNATDP1PIM1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |