Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 7/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.31 |
| ▸ | FABP2 | P12104 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126895 | 0.81 | MTNR1A (0.39) | CD274CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL1127241 | 0.63 | RPA1 (0.43) | KMT2AMEN1LMNACYP1A2MAPT | |
| SCHEMBL1127001 | 0.60 | ADORA3 (0.39) | KMT2AMEN1TSHRCYP1A2MAPT | |
| SCHEMBL15162096 | 0.60 | THRB (0.39) | KMT2APTGS1MEN1PTGS2FABP2 | |
| SCHEMBL1126648 | 0.59 | CSF1R (0.37) | KMT2APTGESMEN1LMNACYP1A2 | |
| SCHEMBL1126905 | 0.58 | SMN1; SMN2 (0.36) | CD274KMT2APTGS1MEN1PTGS2 | |
| SCHEMBL12327240 | 0.58 | SIGMAR1 (0.54) | KMT2AMEN1ADRA2BADORA2AADORA1 | |
| SCHEMBL13242159 | 0.58 | SIGMAR1 (0.54) | KMT2AMEN1ADRA2BADORA2AADORA1 | |
| SCHEMBL998326 | 0.57 | BCAT2 (0.59) | KMT2AMEN1TSHRLMNAGAA | |
| SCHEMBL20568185 | 0.57 | ALDH1A1 (0.46) | KMT2AMEN1CYP1A2HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |