SCHEMBL1128027

SCHEMBL1128027

C=CC[S+](CC=C)Cc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.37
CALM1 P0DP23 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
GAA P10253 1/20 0.34
TSHR P16473 4/20 0.33
ALDH1A1 P00352 3/20 0.33
LOXL2 Q9Y4K0 2/20 0.33
IDO1 P14902 1/20 0.33
TP53 P04637 1/20 0.33
TRPA1 O75762 1/20 0.33
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
ALOX12 P18054 1/20 0.32
CASP1 P29466 1/20 0.32
HSD17B10 Q99714 1/20 0.32
ADH1B P00325 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
ADH7 P40394 1/20 0.31
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11863562 0.95 MAOB (0.37) MAOBCALM1SMN1; SMN2GAATSHR
Bromide SCHEMBL11619420 0.93 MAOB (0.36) MAOBCALM1SMN1; SMN2GAATSHR
SCHEMBL9496784 0.90 MAOB (0.33) MAOBCALM1SMN1; SMN2GAATSHR
SCHEMBL6915524 0.78 SMN1; SMN2 (0.37) MAOBCALM1SMN1; SMN2GAATSHR
SCHEMBL11530031 0.78 LMNA (0.41) ALDH1A1HPGDHSD17B10CNR2
SCHEMBL247179 0.77 CALM1 (0.50) MAOBCALM1SMN1; SMN2TSHRALDH1A1
Bromide SCHEMBL10885367 0.75 CALM1 (0.47) MAOBCALM1SMN1; SMN2TSHRALDH1A1
Iodide SCHEMBL10884305 0.75 CALM1 (0.47) MAOBCALM1SMN1; SMN2TSHRALDH1A1
SCHEMBL9651699 0.71 ALDH1A1 (0.38) ALDH1A1
SCHEMBL9498864 0.70 CALM1 (0.43) MAOBCALM1SMN1; SMN2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0544842-A4 ELECTRON BEAM CURABLE EPOXY COMPOSITIONS 1993-07-21 EP claimed
EP-0544842-A1 ELECTRON BEAM CURABLE EPOXY COMPOSITIONS CRIVELLO, James V. (US) 1993-06-09 EP claimed
EP-0316525-B1 POLYAMIDE REVERSE OSMOSIS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1992-12-02 EP claimed
WO-1992012183-A1 ELECTRON BEAM CURABLE EPOXY COMPOSITIONS CRIVELLO JAMES V (US) 1992-07-23 WO claimed
WO-2024063044-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM 日産化学株式会社 2024-03-28 WO disclosed
CN-117716295-A Composition for forming silicon-containing resist underlayer film and silicon-containing resist underlayer film 日产化学株式会社 2024-03-15 CN disclosed
US-11926581-B2 Sulfonium salt, photoacid generator, curable composition, and resist composition SAN-APRO LIMITED (JP) 2024-03-12 US disclosed
CN-117460995-A Composition for forming underlayer film of silicon-containing resist 日产化学株式会社 2024-01-26 CN disclosed
WO-2024019064-A1 SILICON-CONTAINING RESIST UNDERLAYER FILM-FORMING COMPOSITION CONTAINING POLYFUNCTIONAL SULFONIC ACID 日産化学株式会社 2024-01-25 WO disclosed
WO-2024009993-A1 METHOD OF MANUFACTURING LAMINATE AND METHOD OF MANUFACTURING SEMICONDUCTOR ELEMENT 日産化学株式会社 2024-01-11 WO disclosed
US-20230100642-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION, AND RESIST COMPOSITION SAN-APRO LTD. (JP) 2023-03-30 US disclosed
EP-4122915-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION, AND RESIST COMPOSITION San-Apro Ltd. (JP) 2023-01-25 EP disclosed
EP-2284165-B1 SULFONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION SAN APRO LTD (JP) 2013-02-20 EP disclosed
US-8278030-B2 Sulfonium salt, photoacid generator, and photocurable composition and cured body thereof SAN-APRO LIMITED (JP) 2012-10-02 US disclosed
EP-2399905-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION San-Apro Limited (JP) 2011-12-28 EP disclosed
US-20110300482-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION SAN-APRO, LTD (JP) 2011-12-08 US disclosed
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF SAN-APRO LIMITED (JP) 2011-02-17 US disclosed
EP-2284165-A1 PHOSPHONIUM SALT, PHOTOACID GENERATOR, PHOTO-CURABLE COMPOSITION, AND CURED PRODUCT OF THE PHOTO-CURABLE COMPOSITION San-Apro Limited (JP) 2011-02-16 EP disclosed
EP-0331496-B1 POLYFLUORIDE SULFONIUM COMPOUNDS AND POLYMERIZATION INITIATOR THEREOF SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1992-09-16 EP disclosed
EP-0331496-A1 Polyfluoride sulfonium compounds and polymerization initiator thereof SANSHIN KAGAKU KOGYO CO., LTD. (JP) 1989-09-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110039205-A1 SULFONIUM SALT, PHOTOACID GENERATOR, AND PHOTOCURABLE COMPOSITION AND CURED BODY THEREOF ARSA, ASIC1, TST MAOB 4143/4885CALM1 2089/4885SMN1; SMN2 1788/4885
US-11926581-B2 Sulfonium salt, photoacid generator, curable composition, and resist composition H1-0, SPIN1, IK MAOB 4156/4885CALM1 1621/4885SMN1; SMN2 1364/4885
US-20230100642-A1 SULFONIUM SALT, PHOTOACID GENERATOR, CURABLE COMPOSITION, AND RESIST COMPOSITION TIPRL, SPIN1, SPIN2B MAOB 4673/4885CALM1 1195/4885SMN1; SMN2 1402/4885
US-20110300482-A1 SULFONIUM SALT, PHOTO-ACID GENERATOR, AND PHOTOSENSITIVE RESIN COMPOSITION ASIC1, H1-0, IK MAOB 4253/4885CALM1 2246/4885SMN1; SMN2 2221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.