Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11285847 | 0.81 | DHFR (0.39) | MEN1KMT2AMAPK1MAPTUSP2 | |
| SCHEMBL2461750 | 0.74 | XDH (0.48) | MEN1KMT2AMAPTALDH1A1CYP3A4 | |
| SCHEMBL8955160 | 0.74 | CYP1A2 (0.66) | MEN1KMT2AMAPK1MAPTUSP2 | |
| SCHEMBL9489328 | 0.73 | DHFR (0.48) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL11660801 | 0.73 | GABRA1 (0.45) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL2372640 | 0.73 | ALDH1A1 (1.00) | MEN1KMT2AMAPK1MAPTUSP2 | |
| SCHEMBL240977 | 0.72 | ALOX15 (0.53) | MEN1KMT2AMAPK1ALDH1A1CYP3A4 | |
| SCHEMBL13259833 | 0.72 | CYP2C19 (0.53) | MEN1KMT2AMAPK1CYP1A2CYP2D6 | |
| SCHEMBL9260316 | 0.71 | PTPRB (0.49) | MEN1KMT2AMAPTALDH1A1NPSR1 | |
| SCHEMBL11579327 | 0.71 | KDM4E (0.41) | MEN1KMT2AMAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4333868-A | Phosphite ester stabilizers | CIBA-GEIGY CORPORATION (US) | 1982-06-08 | — | — | US | disclosed |
| US-4132702-A | Phenol esters and amides and polymers stabilized therewith | CIBA-GEIGY CORPORATION (US) | 1979-01-02 | — | — | US | disclosed |