SCHEMBL11315211

SCHEMBL11315211

O=S(=O)([O-])CC(O)CCCl.[Na+]

nearest known ligand 0.00

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23530434 0.81 CA1 (0.36)
SCHEMBL29074252 0.81 CA1 (0.36)
SCHEMBL272976 0.81 CA1 (0.36)
Water SCHEMBL4418329 0.79 CA1 (0.35)
SCHEMBL15754774 0.77 NFKB1 (0.38)
Lithium Ion SCHEMBL28670483 0.76 CA1 (0.36)
Potassium Ion SCHEMBL28357766 0.76 CA1 (0.36)
SCHEMBL11222107 0.76 SLC22A6 (0.36)
SCHEMBL11315229 0.74 SLC22A6 (0.34)
SCHEMBL9392655 0.74 NFKB1 (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102161761-B Preparation method of amphoteric ion polymer UNIV ZHEJIANG GONGSHANG 2012-08-22 CN claimed
CN-102161761-A Preparation method of amphoteric ion polymer UNIV ZHEJIANG GONGSHANG 2011-08-24 CN claimed
EP-2874713-B1 PROCESS TO PRODUCE FLUORINATED BETAINES DU PONT (US) 2016-06-15 EP disclosed
EP-2874713-A1 PROCESS TO PRODUCE FLUORINATED BETAINES E. I. du Pont de Nemours and Company (US) 2015-05-27 EP disclosed
CN-104470589-A Process to produce fluorinated betaines DU PONT 2015-03-25 CN disclosed
US-8809577-B2 Process to produce fluorinated betaines E I DU PONT DE NEMOURS AND COMPANY (US) 2014-08-19 US disclosed
US-20140024855-A1 PROCESS TO PRODUCE FLUORINATED BETAINES E I DU PONT DE NEMOURS AND COMPANY (US) 2014-01-23 US disclosed
WO-2014014810-A1 PROCESS TO PRODUCE FLUORINATED BETAINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-01-23 WO disclosed
CN-102161761-B Preparation method of amphoteric ion polymer UNIV ZHEJIANG GONGSHANG 2012-08-22 CN disclosed
CN-102161761-A Preparation method of amphoteric ion polymer UNIV ZHEJIANG GONGSHANG 2011-08-24 CN disclosed
US-4246194-A HYDROGEN ION BUFFERS USEFUL IN BIOLOGICAL RESEARCH RESEARCH ORGANICS, INC. (US) 1981-01-20 US disclosed
US-4169950-A AMINO-HYDROXY-ALKYL SULFONIC ACID ZWITTERIONS RESEARCH ORGANICS (US) 1979-10-02 US disclosed