Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HNF4A | P41235 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1132588 | 0.72 | LMNA (0.49) | FOLH1MYCCYP3A4CYP2C9ALOX12 | |
| SCHEMBL27478110 | 0.71 | TRPA1 (0.49) | TRPA1CYP3A4KDM4EALDH1A1HSD17B10 | |
| SCHEMBL1773148 | 0.69 | MEN1 (0.40) | KDM4EALDH1A1GAAMEN1USP2 | |
| SCHEMBL2552199 | 0.69 | MEN1 (0.40) | KDM4EALDH1A1GAAMEN1USP2 | |
| SCHEMBL36145 | 0.69 | ALDH1A1 (0.72) | FOLH1MYCCYP3A4CYP2C9ALOX12 | |
| SCHEMBL30028907 | 0.69 | ALDH1A1 (0.72) | FOLH1MYCCYP3A4CYP2C9ALOX12 | |
| Hydrochloric Acid SCHEMBL1681943 | 0.67 | ALDH1A1 (0.68) | FOLH1MYCCYP3A4CYP2C9ALOX12 | |
| SCHEMBL2830888 | 0.67 | ALDH1A1 (0.68) | FOLH1MYCCYP3A4CYP2C9ALOX12 | |
| Hydrochloric Acid SCHEMBL10888462 | 0.67 | ALDH1A1 (0.68) | FOLH1MYCCYP3A4CYP2C9ALOX12 | |
| Hydrochloric Acid SCHEMBL7579852 | 0.67 | ALDH1A1 (0.68) | FOLH1MYCCYP3A4CYP2C9ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8431613-B2 | Memory fixation accelerator | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2013-04-30 | — | — | US | disclosed |
| US-20120214763-A1 | MEMORY FIXATION ACCELERATOR | KEMPHYS LTD. (JP) | 2012-08-23 | — | — | US | disclosed |
| US-8198329-B2 | Memory consolidation promoting agent and method of use | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2012-06-12 | — | — | US | disclosed |
| US-8168677-B2 | Method for treatment of inflammatory bowel disease | KEMPHYS LTD. (JP) | 2012-05-01 | — | — | US | disclosed |
| US-7902260-B2 | Using a retinoid such as 4-((5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalenyl)carbamoyl)benzoic acid | KEMPHYS LTD. (JP) | 2011-03-08 | — | — | US | disclosed |
| EP-2286807-A2 | Medicament for preventive and/or therapeutic treatment of adhesion of bowel | Kemphys Ltd. (JP) | 2011-02-23 | — | — | EP | disclosed |
| US-20100324134-A1 | MEDICAMENT FOR PREVENTIVE AND/OR THERAPEUTIC TREATMENT OF BOWEL DISEASE | KEMPHYS LTD. (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20100004203-A1 | MEDICAMENT FOR PREVENTIVE AND/OR THERAPEUTIC TREATMENT OF BOWEL DISEASE | KEMPHYS LTD. (JP) | 2010-01-07 | — | — | US | disclosed |
| EP-2127645-A1 | PHARMACEUTICAL AGENT FOR PREVENTION AND/OR TREATMENT OF LOWER URINARY TRACT SYMPTOM | Kemphys Ltd. (JP) | 2009-12-02 | — | — | EP | disclosed |
| US-20090281184-A1 | PHARMACEUTICAL FOR PREVENTION AND TREATMENT OF OPHTHALMIC DISEASE INDUCED BY IN-CREASE IN VASOPERMEABILITY | SAPPORO MEDICAL UNIVERSITY (JP) | 2009-11-12 | — | — | US | disclosed |
| US-20080255069-A1 | Medicament for Preventive and/or Therapeutic Treatment of Bowel Disease | R & R INC. (JP) | 2008-10-16 | — | — | US | disclosed |
| US-20080207768-A1 | MEDICAMENT FOR PREVENTIVE AND/OR THERAPEUTIC TREATMENT OF LOWER URINARY TRACT SYMPTOM | R&R INC. (JP) | 2008-08-28 | — | — | US | disclosed |
| EP-1938815-A1 | PHARMACEUTICAL FOR PREVENTION AND TREATMENT OF OPHTHALMIC DISEASE INDUCED BY INCREASE IN VASOPERMEABILITY | Sapporo Medical University (JP) | 2008-07-02 | — | — | EP | disclosed |
| US-20080139842-A1 | Medicament for preventive and/or therapeutic treatment of diseases with secretory disorder | R&R INC. (JP) | 2008-06-12 | — | — | US | disclosed |
| EP-1930001-A1 | PHARMACEUTICAL FOR USE IN PREVENTION AND/OR TREATMENT OF BOWEL DISEASE | R & R Inc. (JP) | 2008-06-11 | — | — | EP | disclosed |
| US-20080021108-A1 | Memory Fixation Accelerator | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2008-01-24 | — | — | US | disclosed |
| EP-1733722-A1 | MEMORY FIXATION ACCELERATOR | Research Foundation Itsuu Laboratory (JP) | 2006-12-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207768-A1 | MEDICAMENT FOR PREVENTIVE AND/OR THERAPEUTIC TREATMENT OF LOWER URINARY TRACT SYMPTOM | RARG, RARB, RARA | TRPA1 2383/4885FOLH1 28/4885MYC 4345/4885 |
| US-20080255069-A1 | Medicament for Preventive and/or Therapeutic Treatment of Bowel Disease | FABP2, RARG, RARA | TRPA1 3083/4885FOLH1 434/4885MYC 3180/4885 |
| US-20120214763-A1 | MEMORY FIXATION ACCELERATOR | BDNF, RXRA, RARA | TRPA1 4015/4885FOLH1 1995/4885MYC 3490/4885 |
| US-20100324134-A1 | MEDICAMENT FOR PREVENTIVE AND/OR THERAPEUTIC TREATMENT OF BOWEL DISEASE | FABP2, RARG, RARA | TRPA1 3083/4885FOLH1 434/4885MYC 3180/4885 |
| US-20080021108-A1 | Memory Fixation Accelerator | BDNF, RARA, RXRA | TRPA1 4077/4885FOLH1 1934/4885MYC 3529/4885 |
| US-20080139842-A1 | Medicament for preventive and/or therapeutic treatment of diseases with secretory disorder | RARA, RBP1, RARG | TRPA1 3447/4885FOLH1 2924/4885MYC 4464/4885 |
| US-20100004203-A1 | MEDICAMENT FOR PREVENTIVE AND/OR THERAPEUTIC TREATMENT OF BOWEL DISEASE | FABP2, RARG, RARA | TRPA1 3083/4885FOLH1 434/4885MYC 3180/4885 |
| US-20090281184-A1 | PHARMACEUTICAL FOR PREVENTION AND TREATMENT OF OPHTHALMIC DISEASE INDUCED BY IN-CREASE IN VASOPERMEABILITY | RBP4, RBP1, ALDH1A2 | TRPA1 1870/4885FOLH1 529/4885MYC 2998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.