SCHEMBL1396175

SCHEMBL1396175

C=CCC1=CC(C(C)(C)C2C=C(CC=C)c3cccc4cccc2c34)c2cccc3cccc1c23

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32
MTNR1A P48039 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133136 0.78 GABRA1 (0.34) GABRA1GABRB2
SCHEMBL4565339 0.67 KMT2A (0.47) GABRA1GABRB2MTNR1A
SCHEMBL11819501 0.67 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL7718899 0.65 HTR6 (0.36)
SCHEMBL3764804 0.65 GABRA1 (0.33) GABRA1GABRB2
SCHEMBL9323927 0.65 GABRA1 (0.40) GABRA1GABRB2MTNR1A
SCHEMBL10915787 0.63 KDM4E (0.31)
SCHEMBL28085018 0.62
SCHEMBL6445149 0.62 HTR6 (0.39)
SCHEMBL822007 0.62 TOP2A (0.34) GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2658835-B1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL CO (US) 2016-08-17 EP disclosed
EP-2044093-B1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME CHEVRON PHILLIPS CHEMICAL CO (US) 2014-12-03 EP disclosed
EP-2658835-A1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2013-11-06 EP disclosed
US-8334420-B2 Selectivity for hexene and octene from ethylene; polymerization inhibitor containing chromium, titanium and vanadium CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-12-18 US disclosed
WO-2012092415-A1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-07-05 WO disclosed
US-20120172645-A1 Olefin Oligomerization catalysts and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-07-05 US disclosed
EP-2289901-A1 Olefin oligomerization catalysts and methods of using same Chevron Phillips Chemical Company LP (US) 2011-03-02 EP disclosed
EP-2044093-A2 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME Chevron Phillips Chemical Company LP (US) 2009-04-08 EP disclosed
US-20080207857-A1 Olefin Oligomerization Catalysts and Methods of Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-08-28 US disclosed
US-7378537-B2 Olefin oligomerization catalysts and methods of using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-05-27 US disclosed
WO-2008014139-A2 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-01-31 WO disclosed
US-20080027188-A1 OLEFIN OLIGOMERIZATION CATALYSTS AND METHODS OF USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2008-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120172645-A1 Olefin Oligomerization catalysts and Methods of Making and Using Same COG7, COG8, COG4 GABRA1 3705/4885GABRB2 4182/4885MTNR1A 2897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.