Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4831885 | 0.83 | PTGS2 (0.42) | CYP1A2RAB9AKMO | |
| SCHEMBL5327938 | 0.83 | ACHE (0.39) | CYP1A2RAB9A | |
| SCHEMBL5326217 | 0.83 | ACHE (0.39) | ALDH1A1RAB9AKMOMAPT | |
| SCHEMBL1134861 | 0.82 | — | — | |
| SCHEMBL5330919 | 0.79 | CNR2 (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL5327982 | 0.79 | CYP11B2 (0.50) | CYP11B1CYP11B2 | |
| SCHEMBL5321545 | 0.79 | PTGS2 (0.46) | KDM4EALDH1A1MAPK1RAB9ACYP17A1 | |
| SCHEMBL27627863 | 0.78 | KDM1A (0.38) | MAOBCYP17A1CYP11B1CYP11B2GPR68 | |
| SCHEMBL694755 | 0.77 | ACHE (0.34) | KDM4EALDH1A1RAB9A | |
| SCHEMBL2112958 | 0.76 | TAAR1 (0.42) | MAOBNOTUMHSD17B1HSD17B2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471016-B2 | Process for the preparation of chiral beta amino carboxamide derivatives | SUN PHARMACEUTICAL INDUSTRIES LTD. | 2013-06-25 | — | — | US | claimed |
| EP-2566843-A2 | PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES | Sun Pharmaceutical Industries Limited (IN) | 2013-03-13 | — | — | EP | claimed |
| US-20130041150-A1 | PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES | SUN PHARMACEUTICAL INDUSTRIES LTD (IN) | 2013-02-14 | — | — | US | claimed |
| WO-2011135586-A2 | PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES | SUN PHARMACEUTICAL INDUSTRIES LTD. (IN) | 2011-11-03 | — | — | WO | claimed |
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | claimed |
| CN-104789111-B | Oligoaniline compound | 日产化学工业株式会社 | 2018-05-01 | — | — | CN | disclosed |
| CN-104821375-B | Oligoaniline compound | 日产化学工业株式会社 | 2018-03-02 | — | — | CN | disclosed |
| US-8946479-B2 | Process for preparation of 4-fluoro-α-[2methyl-l-oxopropyl]-γ-oxo—N—β-diphenylbenzene butane amide | VIJAYASRI ORGANICS LIMITED (IN) | 2015-02-03 | — | — | US | disclosed |
| US-20130184493-A1 | PROCESS FOR PREPARATION OF 4-FLUORO-alpha-[2METHYL-L-OXOPROPYL]-gamma-OXO-N-beta-DIPHENYLBENZENE BUTANE AMIDE | VIJAYASRI ORGANICS LIMITED (IN) | 2013-07-18 | — | — | US | disclosed |
| EP-2285779-B1 | Method for manufacturing aryl carboxamides | BASF SE (DE) | 2013-03-27 | — | — | EP | disclosed |
| EP-2285779-A1 | METHOD FOR MANUFACTURING ARYL CARBOXAMIDES | BASF SE (DE) | 2011-02-23 | — | — | EP | disclosed |
| WO-2009135860-A1 | METHOD FOR MANUFACTURING ARYL CARBOXAMIDES | BASF SE (DE) | 2009-11-12 | — | — | WO | disclosed |
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007135527-A2 | BENZIMIDAZOLYL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184493-A1 | PROCESS FOR PREPARATION OF 4-FLUORO-alpha-[2METHYL-L-OXOPROPYL]-gamma-OXO-N-beta-DIPHENYLBENZENE BUTANE AMIDE | BCKDK, FNTB, HMGCR | MAOB 608/4885NOTUM 254/4885HSD17B1 281/4885 |
| US-20130041150-A1 | PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES | BCAT2, BCAT1, SUCLA2 | MAOB 185/4885NOTUM 979/4885HSD17B1 1490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.