Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20374991 | 0.75 | POLB (0.38) | POLBEPHX1MEN1KMT2AHDAC3 | |
| SCHEMBL12862755 | 0.69 | EPHX1 (0.31) | POLBEPHX1 | |
| SCHEMBL20953659 | 0.68 | MEN1 (0.40) | POLBEPHX1MEN1KMT2A | |
| SCHEMBL153717 | 0.68 | L3MBTL1 (0.42) | POLBEPHX1MEN1KMT2A | |
| SCHEMBL18016462 | 0.66 | ALDH1A1 (0.42) | POLBEPHX1MEN1KMT2A | |
| SCHEMBL8962258 | 0.64 | EPHX1 (0.37) | POLBEPHX1MEN1KMT2A | |
| SCHEMBL2757992 | 0.64 | CA2 (0.48) | POLBEPHX1MEN1KMT2A | |
| SCHEMBL14680931 | 0.64 | EPHX1 (0.37) | POLBEPHX1MEN1KMT2A | |
| SCHEMBL20852999 | 0.64 | EPHX1 (0.37) | POLBEPHX1MEN1KMT2A | |
| SCHEMBL11947831 | 0.64 | EPHX1 (0.37) | POLBEPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655303-B1 | Process for the Controlled Increase in Molecular Weight of Polyethylene or Polyethylene Blends | BASF SE (DE) | 2011-02-23 | — | — | EP | disclosed |
| US-7579411-B2 | Process for the controlled increase in the molecular weight of polyethylenes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2009-08-25 | — | — | US | disclosed |
| US-20080146740-A1 | Process for the controlled increase in the molecular weight of polyethylenes | ROTH MICHAEL | 2008-06-19 | — | — | US | disclosed |
| US-7358365-B2 | Process for the controlled increase in the molecular weight of polyethylenes | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060128903-A1 | Process for the controlled increase in the molecular weight of polyethylenes | ROTH MICHAEL | 2006-06-15 | — | — | US | disclosed |
| EP-1282630-B1 | Process for Reducing the Molecular Weight of Polypropylene Using Hydroxylamine Esters | CIBA SC HOLDING AG (CH) | 2006-05-10 | — | — | EP | disclosed |
| EP-1655303-A2 | Hydroxylamine esters as polimerization initiators | Ciba SC Holding AG (CH) | 2006-05-10 | — | — | EP | disclosed |
| US-7030196-B2 | Process for reducing the molecular weight of polypropylene | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-04-18 | — | — | US | disclosed |
| US-6841703-B2 | Open chain alkoxyamine compounds and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-01-11 | — | — | US | disclosed |
| EP-1100772-B1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | CIBA SC HOLDING AG (CH) | 2004-04-14 | — | — | EP | disclosed |
| US-20030216494-A1 | Hydroxylamine esters as polymerization initiators | CIBA SPECIALTY CHEMICALS CORP. | 2003-11-20 | — | — | US | disclosed |
| US-20030125489-A1 | Open chain alkoxyamine compounds and their use as polymerization regulators | NESVADBA PETER (CH) | 2003-07-03 | — | — | US | disclosed |
| EP-1282630-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | Ciba SC Holding AG (CH) | 2003-02-12 | — | — | EP | disclosed |
| US-6518326-B1 | Open chain alkoxyamine compounds and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-11 | — | — | US | disclosed |
| WO-2001090113-A1 | HYDROXYLAMINE ESTERS AS POLYMERIZATION INITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2001-11-29 | — | — | WO | disclosed |
| EP-1100772-A1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | Ciba SC Holding AG (CH) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000007981-A1 | OPEN CHAIN ALKOXYAMINE COMPOUNDS AND THEIR USE AS POLYMERIZATION REGULATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125489-A1 | Open chain alkoxyamine compounds and their use as polymerization regulators | ALOX5, PTGER1, ALOX12 | POLB 355/4885EPHX1 174/4885MEN1 4480/4885 |
| US-20030216494-A1 | Hydroxylamine esters as polymerization initiators | PNMT, HPGDS, HAAO | POLB 667/4885EPHX1 106/4885MEN1 3964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.