Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2N | P61088 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407185 | 0.77 | L3MBTL1 (0.58) | L3MBTL1SMN1; SMN2KMT2AMAPTHPGD | |
| SCHEMBL4516870 | 0.76 | L3MBTL1 (0.55) | L3MBTL1SMN1; SMN2KMT2ANPC1RAB9A | |
| SCHEMBL27585716 | 0.76 | L3MBTL1 (0.60) | L3MBTL1SMN1; SMN2KMT2AHPGDHSD17B10 | |
| SCHEMBL3407740 | 0.73 | NPC1 (0.49) | SMN1; SMN2KMT2ANPC1RAB9AMAPT | |
| SCHEMBL6973438 | 0.72 | HSD17B10 (0.66) | SMN1; SMN2KMT2ANPC1MAPTLMNA | |
| SCHEMBL13713080 | 0.71 | ADORA3 (0.61) | L3MBTL1SMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL9728959 | 0.71 | RAB9A (0.72) | SMN1; SMN2KMT2ANPC1RAB9AMAPT | |
| SCHEMBL22686985 | 0.71 | LMNA (0.76) | SMN1; SMN2KMT2AMAPTLMNAMEN1 | |
| SCHEMBL7593290 | 0.69 | MEN1 (0.77) | L3MBTL1SMN1; SMN2KMT2ANPSR1MAPT | |
| SCHEMBL6257175 | 0.69 | KMT2A (0.69) | SMN1; SMN2KMT2ANPSR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4268511-A | DIURETICS, MUSCLE RELAXANTS | BERRI-BALZAC (FR) | 1981-05-19 | — | — | US | disclosed |