Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 9/20 | 0.43 |
| ▸ | FDPS | P14324 | 7/20 | 0.42 |
| ▸ | STAT1 | P42224 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819177 | 0.93 | NPC1 (0.48) | NPC1RAB9ATSHRSMYD3FDPS | |
| SCHEMBL9790653 | 0.73 | TRPM8 (0.56) | NPC1RAB9ATSHRFDPS | |
| SCHEMBL11401437 | 0.72 | FDPS (0.47) | NPC1RAB9ATSHRFDPS | |
| SCHEMBL11641528 | 0.70 | RAB9A (0.61) | NPC1RAB9ATSHRSMYD3STAT1 | |
| SCHEMBL9819252 | 0.70 | FDPS (0.47) | FDPS | |
| SCHEMBL9819467 | 0.69 | NPC1 (0.46) | NPC1RAB9ATSHRSMYD3STAT1 | |
| SCHEMBL9819238 | 0.68 | FDPS (0.57) | NPC1RAB9AFDPS | |
| SCHEMBL9819343 | 0.68 | RAB9A (0.49) | NPC1RAB9AFDPS | |
| SCHEMBL9819288 | 0.66 | FDPS (0.51) | NPC1RAB9AFDPS | |
| SCHEMBL9819301 | 0.66 | FDPS (0.41) | RAB9AFDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282320-B1 | BISPHOSPHONIC ACID DERIVATIVES AND MEDICINES CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-12-11 | — | — | EP | claimed |
| US-4973576-A | ANTIARTHRITIC AGENTS, TREATMENT OF HYPERCALCEMIA | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-11-27 | — | — | US | claimed |
| EP-0282320-A1 | Bisphosphonic acid derivatives and medicines containing the same | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-14 | — | — | EP | claimed |
| EP-0282320-B1 | BISPHOSPHONIC ACID DERIVATIVES AND MEDICINES CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1991-12-11 | — | — | EP | disclosed |
| US-4973576-A | ANTIARTHRITIC AGENTS, TREATMENT OF HYPERCALCEMIA | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1990-11-27 | — | — | US | disclosed |
| EP-0282320-A1 | Bisphosphonic acid derivatives and medicines containing the same | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-09-14 | — | — | EP | disclosed |