Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461822 | 0.84 | ALDH1A1 (0.41) | ALDH1A1CES2CES1CA12CA1 | |
| Phenol SCHEMBL27620142 | 0.81 | CA12 (0.42) | ALDH1A1CES2CES1CA12CA1 | |
| Benzenethiol SCHEMBL27437857 | 0.79 | ALDH1A1 (0.38) | ALDH1A1CES2CES1HDAC1 | |
| SCHEMBL531337 | 0.77 | CES2 (0.52) | ALDH1A1CES2CES1CA12CA1 | |
| SCHEMBL5515689 | 0.77 | ALDH1A1 (0.36) | ALDH1A1CES2CES1CA12CA1 | |
| SCHEMBL29674864 | 0.77 | ALDH1A1 (0.48) | ALDH1A1CES2CES1CA12CA1 | |
| SCHEMBL101668 | 0.77 | ALDH1A1 (0.48) | ALDH1A1CES2CES1CA12CA1 | |
| SCHEMBL9154640 | 0.74 | ALDH1A1 (0.46) | ALDH1A1CES2CES1CA1CA2 | |
| SCHEMBL998262 | 0.73 | ALDH1A1 (0.38) | ALDH1A1CES2CES1CA12CA1 | |
| SCHEMBL29402276 | 0.72 | ALDH1A1 (0.39) | ALDH1A1CES2CES1LMNATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119707773-A | Preparation method and application of maleimide structure-containing compound | 中国农业大学 | 2025-03-28 | — | — | CN | claimed |
| CN-118930473-A | Preparation method of 4,6, 7-trifluoro-1H-indole-2-carboxylic acid | 上海鲲博玖瑞医药科技发展有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-116396204-B | Preparation method of 4,6, 7-trifluoro-1H-indole-2-carboxylic acid | 无锡科华生物科技有限公司 | 2024-09-24 | — | — | CN | claimed |
| CN-118183708-A | Method for preparing fluorocarbon material by using fluorine-containing polymer | 重庆大学锂电及新材料遂宁研究院 | 2024-06-14 | — | — | CN | claimed |
| CN-116396204-A | Preparation method of 4,6,7-trifluoro-1H-indole-2-carboxylic acid | 无锡科华生物科技有限公司 | 2023-07-07 | — | — | CN | claimed |
| WO-2007130712-A1 | SUBSTITUTED DIPIPERIDINE AS CCR2 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | JANSSEN PHARMACEUTICA, NV (BE) | 2007-11-15 | — | — | WO | claimed |
| US-20070197590-A1 | SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS | JANSSEN PHARMACEUTCA N.V. (BE) | 2007-08-23 | — | — | US | claimed |
| US-12384778-B2 | Pyrazolopyridine compounds and uses thereof | INCYTE CORPORATION (US) | 2025-08-12 | — | — | US | disclosed |
| CN-120058508-A | Preparation method of 2,4, 5-trifluoro-phenylacetic acid | 浙江昌海制药有限公司 | 2025-05-30 | — | — | CN | disclosed |
| CN-119707773-A | Preparation method and application of maleimide structure-containing compound | 中国农业大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-118930473-A | Preparation method of 4,6, 7-trifluoro-1H-indole-2-carboxylic acid | 上海鲲博玖瑞医药科技发展有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-118930473-A | Preparation method of 4,6, 7-trifluoro-1H-indole-2-carboxylic acid | 上海鲲博玖瑞医药科技发展有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-116396204-B | Preparation method of 4,6, 7-trifluoro-1H-indole-2-carboxylic acid | 无锡科华生物科技有限公司 | 2024-09-24 | — | — | CN | disclosed |
| WO-2000024719-A1 | PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2000-05-04 | — | — | WO | disclosed |
| WO-1999010331-A1 | ARYLPYRIDAZINONES AS PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE BIOSYNTHESIS INHIBITORS | ABBOTT LABORATORIES (US) | 1999-03-04 | — | — | WO | disclosed |
| EP-0596130-B1 | PRODUCTION OF 2-HALO-3,5-DIFLUOROANILINE, INTERMEDIATE FOR PRODUCING THE SAME, AND PRODUCTION OF SAID INTERMEDIATE | SDS BIOTECH CORP (JP) | 1997-09-24 | — | — | EP | disclosed |
| EP-0596130-A1 | PRODUCTION OF 2-HALO-3,5-DIFLUOROANILINE, INTERMEDIATE FOR PRODUCING THE SAME, AND PRODUCTION OF SAID INTERMEDIATE | SDS Biotech K.K. (JP) | 1994-05-11 | — | — | EP | disclosed |
| US-4873357-A | Trifluoro acetyl-cyano-aniline intermediates for dopamine-βhydroxylase inhibitors | SMITHKLINE BECKMAN CORPORATION (US) | 1989-10-10 | — | — | US | disclosed |
| US-4719223-A | ENZYME INHIBITORS, HYPOTENSIVE, CARDIOTONIC DIURETIC | SMITHKLINE BECKMAN CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| EP-0221778-A2 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BECKMAN CORPORATION (US) | 1987-05-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12384778-B2 | Pyrazolopyridine compounds and uses thereof | PDXK, PCK1, PGK1 | ALDH1A1 2205/4885CES2 3190/4885CES1 1055/4885 |
| US-20070197590-A1 | SUBSTITUTED DIPIPERIDINE CCR2 ANTAGONISTS | CCR2, CCR1, CCR5 | ALDH1A1 905/4885CES2 2502/4885CES1 2047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.