Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.37 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 6/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1552115 | 1.00 | CES2 (0.39) | CES2CA1GPR84CA2CES1 | |
| SCHEMBL28919474 | 1.00 | CES2 (0.39) | CES2CA1GPR84CA2CES1 | |
| SCHEMBL7967481 | 1.00 | CES2 (0.39) | CES2CA1GPR84CA2CES1 | |
| SCHEMBL2729135 | 1.00 | CES2 (0.39) | CES2CA1GPR84CA2CES1 | |
| SCHEMBL10993074 | 1.00 | CES2 (0.39) | CES2CA1GPR84CA2CES1 | |
| SCHEMBL339202 | 1.00 | CES2 (0.39) | CES2CA1GPR84CA2CES1 | |
| SCHEMBL2957022 | 1.00 | CES2 (0.39) | CES2CA1GPR84CA2CES1 | |
| SCHEMBL219970 | 1.00 | CES2 (0.39) | CES2CA1GPR84CA2CES1 | |
| SCHEMBL1666274 | 1.00 | CES2 (0.39) | CES2CA1GPR84CA2CES1 | |
| SCHEMBL9651109 | 1.00 | CES2 (0.39) | CES2CA1GPR84CA2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230746-A | SULFATE FOAMING AGENT, TERTIARY AMINE OR QUATERNARY SALT DISPERSANT, SULFOSUCCINATE STABILIZER | GAF CORPORATION (US) | 1980-10-28 | — | — | US | disclosed |
| US-4208485-A | ORGANIC SULFATE, SULFOSUCCINIC ACID DERIVATIVES, AND AN ALKYLENEOXY AMINE | GAF CORPORATION (US) | 1980-06-17 | — | — | US | disclosed |
| US-4198316-A | Foaming composition for textile finishing and coatings | GAF CORPORATION (US) | 1980-04-15 | — | — | US | disclosed |