Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Binedaline SCHEMBL49440 | 0.86 | L3MBTL1 (0.42) | HTR6KDR | |
| Binedaline SCHEMBL5957158 | 0.85 | L3MBTL1 (0.41) | HTR6KDRHTT | |
| SCHEMBL11452382 | 0.79 | L3MBTL1 (0.40) | HTR6KDRKDM4E | |
| SCHEMBL11452293 | 0.75 | L3MBTL1 (0.39) | HTR6POLBRAD52GAARAB9A | |
| SCHEMBL7549158 | 0.69 | KDR (0.69) | HTR6FLT4KDRFLT3 | |
| SCHEMBL11464649 | 0.68 | HTR6 (0.46) | HTR6KDM4EALDH1A1HTTRAB9A | |
| SCHEMBL11399845 | 0.68 | DNM2 (0.42) | POLBKDM4EALDH1A1 | |
| SCHEMBL11465337 | 0.65 | RXRA (0.41) | HTR6TSPOSRCFLT3KDM4E | |
| SCHEMBL28984412 | 0.65 | L3MBTL1 (0.77) | HTR6KDM4E | |
| SCHEMBL11461068 | 0.65 | CSF1R (0.39) | HTR6KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4204998-A | N-Amino indole derivatives having pharmacological activity | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-05-27 | — | — | US | claimed |
| US-4204998-A | N-Amino indole derivatives having pharmacological activity | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-05-27 | — | — | US | disclosed |