Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11452382 | 0.79 | L3MBTL1 (0.40) | KDM4EL3MBTL1 | |
| Binedaline SCHEMBL49440 | 0.79 | L3MBTL1 (0.42) | L3MBTL1MEN1KMT2A | |
| Binedaline SCHEMBL29393236 | 0.79 | L3MBTL1 (0.42) | L3MBTL1MEN1KMT2A | |
| SCHEMBL11452293 | 0.78 | L3MBTL1 (0.39) | L3MBTL1POLBSLC6A2 | |
| Binedaline SCHEMBL5957158 | 0.78 | L3MBTL1 (0.41) | L3MBTL1 | |
| SCHEMBL11464649 | 0.72 | HTR6 (0.46) | KDM4EALDH1A1SMN1; SMN2L3MBTL1 | |
| Biphenyl SCHEMBL5716264 | 0.68 | DRD2 (0.58) | KDM4EALDH1A1SMN1; SMN2SIGMAR1 | |
| Biphenyl SCHEMBL7742046 | 0.68 | SIGMAR1 (0.59) | KDM4EALDH1A1SMN1; SMN2SIGMAR1 | |
| SCHEMBL11465337 | 0.66 | RXRA (0.41) | KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11452275 | 0.65 | MAT2A (0.50) | KDM4ESMN1; SMN2POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042054-A1 | 1-Amino-3-phenyl indoles, their salts and medicaments containing them | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1981-12-23 | — | — | EP | disclosed |