Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3912578 | 0.81 | NPC1 (0.35) | ALDH1A1L3MBTL1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL2013259 | 0.78 | GPR3 (0.39) | L3MBTL1GAASMN1; SMN2NPC1MAPT | |
| SCHEMBL7839044 | 0.78 | PLA2G7 (0.40) | ALDH1A1L3MBTL1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL6655477 | 0.75 | MAOA (0.42) | ALDH1A1L3MBTL1GAAKDM4EMAOB | |
| SCHEMBL8729219 | 0.75 | L3MBTL1 (0.38) | ALDH1A1L3MBTL1SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL4608864 | 0.75 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1GAASMN1; SMN2KDM4E | |
| SCHEMBL7049757 | 0.75 | ACHE (0.38) | ALDH1A1SMN1; SMN2TDP1CYP3A4ALOX15 | |
| SCHEMBL16020781 | 0.74 | ACHE (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6607471 | 0.74 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1GAASMN1; SMN2KDM4E | |
| SCHEMBL8379027 | 0.74 | HSD11B1 (0.44) | ALDH1A1HSD17B10TDP1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166059-A | ALKALI-FAST DISAZO DISULFIMIDE DYES | CROMPTON & KNOWLES CORPORATION (US) | 1979-08-28 | — | — | US | disclosed |