SCHEMBL2013259

SCHEMBL2013259

Cc1cc[c]c(-c2ccccc2F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 3/20 0.39
MBNL1 Q9NR56 1/20 0.37
SMN1; SMN2 Q16637 4/20 0.36
HPGD P15428 2/20 0.36
POLB P06746 1/20 0.36
MAPT P10636 1/20 0.36
CASP3 P42574 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
SENP8 Q96LD8 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
ACHE P22303 2/20 0.35
GRM2 Q14416 1/20 0.35
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
MEN1 O00255 1/20 0.34
NFKB1 P19838 1/20 0.34
NFKB2 Q00653 1/20 0.34
KMT2A Q03164 1/20 0.34
RELA Q04206 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2053205 0.86 ACHE (0.35) GPR3ACHEHSD11B1
SCHEMBL434431 0.81 L3MBTL1 (0.38) GPR3MBNL1SMN1; SMN2HPGDCASP3
SCHEMBL3912578 0.81 NPC1 (0.35) SMN1; SMN2HPGDMAPTCASP3NPSR1
SCHEMBL2051071 0.80 ALDH1A1 (0.39) GPR3HPGDACHEMEN1KMT2A
SCHEMBL2053522 0.80 ACHE (0.36) HPGDACHEMEN1KMT2AL3MBTL1
SCHEMBL2049079 0.79 ACHE (0.39) MAPTACHECSNK1DCSNK1EMAPK14
SCHEMBL432357 0.78 GABRP (0.41) GPR3SMN1; SMN2HPGDNPC1RAB9A
SCHEMBL7839044 0.78 PLA2G7 (0.40) SMN1; SMN2HPGDPOLBMAPTGRM2
SCHEMBL11514726 0.78 ALDH1A1 (0.43) SMN1; SMN2MAPTNPC1RAB9AMEN1
SCHEMBL8379027 0.77 HSD11B1 (0.44) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013182433-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-12-12 WO disclosed
EP-2547687-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2013-01-23 EP disclosed
EP-2513067-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2012-10-24 EP disclosed
WO-2011113820-A1 A PROCESS USING GRIGNARD REAGENTS BASF SE (DE) 2011-09-22 WO disclosed
WO-2011073145-A1 METHOD FOR PRODUCING TRIAZOLINTHIONE DERIVATIVES AND INTERMEDIATES THEREOF BASF SE (DE) 2011-06-23 WO disclosed
US-4946493-A FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-08-07 US disclosed
US-4845250-A FUNGICIDES, PLANT GROWTH REGULATORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1989-07-04 US disclosed
US-4507140-A GALLIUM ARSENIDE DOPED WITH GERMANIUM AND TELLURIUM IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-03-26 US disclosed