Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18924216 | 0.86 | TSHR (0.56) | MAPTLMNAGAAPOLBTHRB | |
| SCHEMBL10335263 | 0.82 | HTT (0.49) | MAPTLMNAGAAPOLBL3MBTL1 | |
| SCHEMBL574894 | 0.79 | L3MBTL1 (0.42) | MAPTLMNAL3MBTL1THRBKMT2A | |
| SCHEMBL2211256 | 0.75 | MAPT (0.54) | MAPTLMNAGAAPOLBTHRB | |
| SCHEMBL11536912 | 0.75 | LMNA (0.61) | MAPTLMNAGAAPOLBKMT2A | |
| SCHEMBL20267448 | 0.71 | MAPT (0.50) | MAPTLMNAGAAPOLBTHRB | |
| SCHEMBL14964147 | 0.71 | NAAA (0.40) | MAPTLMNAPOLBL3MBTL1KMT2A | |
| SCHEMBL14404822 | 0.70 | MAPT (0.67) | MAPTLMNAGAAL3MBTL1KMT2A | |
| 4-Chloroaniline SCHEMBL11573070 | 0.70 | MAPT (0.57) | MAPTLMNAGAAPOLBTHRB | |
| SCHEMBL2867253 | 0.69 | ABCC8 (0.50) | MAPTLMNAPOLBL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177054-A | PREEMERGENT AND POSTEMERGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-12-04 | — | — | US | disclosed |