Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearyl Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796092 | 1.00 | HCAR2 (0.69) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL11798637 | 1.00 | HCAR2 (0.69) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL9678159 | 1.00 | HCAR2 (0.69) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL11800018 | 1.00 | HCAR2 (0.69) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL11799659 | 1.00 | HCAR2 (0.69) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Stearyl Fumaric Acid SCHEMBL25396 | 1.00 | HCAR2 (0.69) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL9679071 | 1.00 | HCAR2 (0.69) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Stearyl Fumaric Acid SCHEMBL25393 | 1.00 | HCAR2 (0.69) | HCAR2ATMMAPTRAB9ANPSR1 | |
| Hexyl Fumarate SCHEMBL9678755 | 1.00 | HCAR2 (0.69) | HCAR2ATMMAPTRAB9ANPSR1 | |
| SCHEMBL11796079 | 1.00 | HCAR2 (0.69) | HCAR2ATMMAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116242938-B | Determination method of sodium stearyl fumarate impurity | 北京吉洛华制药有限公司 | 2025-05-13 | — | — | CN | claimed |
| CN-116242938-A | Determination method of sodium stearyl fumarate impurity | 北京吉洛华制药有限公司 | 2023-06-09 | — | — | CN | claimed |
| CN-112972400-A | Rapidly disintegrable minodronic acid granules and preparation method thereof | 华侨大学 | 2021-06-18 | — | — | CN | claimed |
| CN-116242938-B | Determination method of sodium stearyl fumarate impurity | 北京吉洛华制药有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-115181216-B | Retanning agent and preparation method thereof | 齐河力厚化工有限公司 | 2023-09-26 | — | — | CN | disclosed |
| CN-116242938-A | Determination method of sodium stearyl fumarate impurity | 北京吉洛华制药有限公司 | 2023-06-09 | — | — | CN | disclosed |
| CN-115181216-A | Retanning agent and preparation method thereof | 齐河力厚化工有限公司 | 2022-10-14 | — | — | CN | disclosed |
| CN-113801167-A | Platinum complex, liposome thereof and application thereof | 沈阳药科大学 | 2021-12-17 | — | — | CN | disclosed |
| CN-108586250-B | Sodium stearyl fumarate auxiliary material and preparation method thereof | 苏州东南药业股份有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-112972400-A | Rapidly disintegrable minodronic acid granules and preparation method thereof | 华侨大学 | 2021-06-18 | — | — | CN | disclosed |
| US-4148665-A | SULFOSUCCINIC ACID OR AMIDE, SODIUM SALT | AMERICAN CYANAMID COMPANY (US) | 1979-04-10 | — | — | US | disclosed |