Stearyl Fumaric Acid

Stearyl Fumaric Acid

SCHEMBL25393

CCCCCCCCCCCCCCCCCCOC(=O)/C=C/C(=O)[O-].[Na+]

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearyl Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.69
ATM Q13315 1/20 0.66
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
NAAA Q02083 1/20 0.48
APP P05067 4/20 0.48
TSHR P16473 3/20 0.47
HPGD P15428 1/20 0.47
HTT P42858 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
EPHX1 P07099 1/20 0.46
PRKCA P17252 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11796092 1.00 HCAR2 (0.69) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL11798637 1.00 HCAR2 (0.69) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9678159 1.00 HCAR2 (0.69) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL11800018 1.00 HCAR2 (0.69) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL11799659 1.00 HCAR2 (0.69) HCAR2ATMMAPTRAB9ANPSR1
Stearyl Fumaric Acid SCHEMBL11545461 1.00 HCAR2 (0.69) HCAR2ATMMAPTRAB9ANPSR1
Stearyl Fumaric Acid SCHEMBL25396 1.00 HCAR2 (0.69) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL9679071 1.00 HCAR2 (0.69) HCAR2ATMMAPTRAB9ANPSR1
Hexyl Fumarate SCHEMBL9678755 1.00 HCAR2 (0.69) HCAR2ATMMAPTRAB9ANPSR1
SCHEMBL11796079 1.00 HCAR2 (0.69) HCAR2ATMMAPTRAB9ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 60695 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144755-A1 Solid Oral Dosage Forms Comprising Tavapadon CEREVEL THERAPEUTICS, LLC (US) 2026-05-28 US claimed
US-20260144779-A1 MODIFIED RELEASE PHARMACEUTICAL FORMULATIONS COMPRISING DEFERIPRONE CHIESI FARMACEUTICI S.P.A. (IT) 2026-05-28 US claimed
US-20260146717-A1 DRAG REDUCTION FORMULATION AND A METHOD FOR PREPARATION THEREOF HINDUSTAN PETROLEUM CORPORATION LIMITED (IN) 2026-05-28 US claimed
EP-4746854-A1 STABLE PHARMACEUTICAL COMPOSITIONS OF A CYP11A1 INHIBITOR ORION CORPORATION (FI) 2026-05-27 EP claimed
EP-4319563-B1 CONTROLLED-RELEASE NICOTINE CHEWING GUM ALTRIA CLIENT SERVICES LLC (US) 2026-05-27 EP claimed
CN-122074579-A Ginseng adventitious root pressed candy and preparation method thereof 2026-05-26 CN claimed
CN-122094683-A Sustained release formulations of Kv7.2/7.3 potassium channel activators 2026-05-26 CN claimed
CN-122075463-A Pharmaceutical composition containing melagatran besylate and preparation method thereof 2026-05-26 CN claimed
CN-122075424-A Bisoprolol fumarate tablet with long-term storage stability and preparation method thereof 2026-05-26 CN claimed
CN-122094690-A Pharmaceutical composition comprising Maraglinib (MARALIXIBAT) and use thereof 2026-05-26 CN claimed
US-4810518-A FOODS, FEEDS, FOOD PROCESSING THOMAS J. LIPTON, INC. (US) 1989-03-07 US claimed
EP-0229938-A1 Food product UNILEVER N.V. (NL) 1987-07-29 EP claimed
EP-0012499-B1 DRY POWDERED NON-DAIRY FOOD COMPOSITION CONTAINING LIQUID FAT R.G.B. LABORATORIES, INC. (US) 1984-03-07 EP claimed
US-4415600-A IONIC EMULSIFIERS OF SODIUM OR CALCIUM LACTYLATED ESTERS OF FATTY ACIDS AND SODIUM STEARYL FUMARATE; MON-AND DIGLYCERIDES SCM CORPORATION (US) 1983-11-15 US claimed
US-4242364-A ENCAPSULATED IN CARBOHYDRATE AND EMULSIFIER MATRIX R.G.B. LABORATORIES, INC. (US) 1980-12-30 US claimed
EP-0012499-A1 Dry powdered non-dairy food composition containing liquid fat R.G.B. LABORATORIES, INC. (US) 1980-06-25 EP claimed
US-4188410-A OIL OR FAT AND EMULSIFIER GENERAL FOODS CORPORATION (US) 1980-02-12 US claimed
EP-0000670-A1 Therapeutic selenium compositions and the use thereof LUNDY RESEARCH LABORATORIES, INC. (US) 1979-02-07 EP claimed
US-3968260-A Product and process for producing dehydrated granular potato product having high cold water adsorption AMERICAN POTATO COMPANY (US) 1976-07-06 US claimed
US-3958033-A FAT, SUGAR, WATER GENERAL FOODS CORPORATION (US) 1976-05-18 US claimed