Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.34 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544982 | 0.89 | TSHR (0.40) | TSHRNPC1RAB9AKCNJ1KCNH2 | |
| SCHEMBL11544871 | 0.79 | PARP1 (0.39) | TSHRMAPTNPC1RAB9APKM | |
| SCHEMBL11545754 | 0.74 | TSHR (0.35) | TSHRMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11545798 | 0.74 | SIRT2 (0.38) | KDM4EALDH1A1MAPK1MEN1CYP1A2 | |
| SCHEMBL11545682 | 0.73 | TSHR (0.36) | TSHRMAPTKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11473861 | 0.73 | ADORA3 (0.39) | MAPTNPC1RAB9ACRHBPHTT | |
| SCHEMBL11545925 | 0.73 | PAX8 (0.44) | TSHRMAPTNPC1KDM4EALDH1A1 | |
| SCHEMBL5202849 | 0.71 | MAPT (0.41) | MAPTPKMKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL11544998 | 0.71 | ALOX5 (0.36) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11549665 | 0.70 | MEN1 (0.43) | TSHRMAPTNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145554-A | BACTERICIDES, MICROBIOCIDES, HERBICIDES, PARASITICDES | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |