Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11543964 | 0.89 | ALDH1A1 (0.43) | MEN1KMT2AATMALDH1A1TSHR | |
| SCHEMBL11545925 | 0.82 | PAX8 (0.44) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11544982 | 0.80 | TSHR (0.40) | KMT2ATSHRCA2NPC1RAB9A | |
| SCHEMBL11573906 | 0.78 | LMNA (0.38) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL11546972 | 0.77 | GLA (0.38) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL11473364 | 0.76 | KMT2A (0.43) | MEN1KMT2AATMALDH1A1ESR1 | |
| SCHEMBL11549663 | 0.73 | CA12 (0.45) | MEN1KMT2AALDH1A1ESR1TSHR | |
| SCHEMBL11545682 | 0.70 | TSHR (0.36) | ALDH1A1TSHRSMN1; SMN2LMNAKDM4E | |
| SCHEMBL11545003 | 0.70 | TSHR (0.40) | MEN1KMT2AALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL11544871 | 0.69 | PARP1 (0.39) | MEN1KMT2AATMALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145554-A | BACTERICIDES, MICROBIOCIDES, HERBICIDES, PARASITICDES | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |