Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 6/20 | 0.32 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CDC20 | Q12834 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11573906 | 0.80 | LMNA (0.38) | GLALMNAMAPTKDM4EMEN1 | |
| SCHEMBL11545754 | 0.78 | TSHR (0.35) | GLALMNATSHRMAPTKDM4E | |
| SCHEMBL11549665 | 0.77 | MEN1 (0.43) | LMNATSHRMAPTKDM4EMEN1 | |
| SCHEMBL11546970 | 0.76 | LMNA (0.36) | GLALMNAMAPTKMT2A | |
| SCHEMBL11472451 | 0.74 | GLA (0.36) | GLALMNAMAPTKDM4EMEN1 | |
| SCHEMBL11545682 | 0.74 | TSHR (0.36) | GLALMNATSHRMAPTKDM4E | |
| SCHEMBL11545925 | 0.73 | PAX8 (0.44) | GLALMNATSHRMAPTKDM4E | |
| SCHEMBL5202849 | 0.72 | MAPT (0.41) | GLALMNAMAPTKDM4EMEN1 | |
| SCHEMBL11544982 | 0.70 | TSHR (0.40) | TSHRPKMKMT2ANPC1 | |
| SCHEMBL11545003 | 0.69 | TSHR (0.40) | TSHRMAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145554-A | BACTERICIDES, MICROBIOCIDES, HERBICIDES, PARASITICDES | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |