Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11430852 | 0.86 | MMP2 (0.60) | MMP2MMP9MMP12ALDH1A1HTT | |
| SCHEMBL29143247 | 0.83 | SIRT1 (0.47) | MMP2MMP9MMP12MAPTALDH1A1 | |
| SCHEMBL11427398 | 0.79 | ALDH1A1 (0.46) | MMP2MMP9MMP12MAPTALDH1A1 | |
| Oxirane SCHEMBL11442758 | 0.76 | SIRT1 (0.41) | MMP2MMP9MMP12MAPTALDH1A1 | |
| SCHEMBL11552435 | 0.76 | SLC6A2 (0.44) | MMP2MMP9MMP12MAPTALDH1A1 | |
| SCHEMBL11554657 | 0.74 | AKR1B1 (0.49) | MMP2MMP9MMP12ALDH1A1HTT | |
| SCHEMBL11400372 | 0.74 | MMP2 (0.38) | MMP2MMP9MMP12ALDH1A1MEN1 | |
| SCHEMBL16200806 | 0.73 | LTA4H (0.61) | MAPTALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL11541636 | 0.73 | BACE1 (0.44) | MMP2MMP9MMP12SMN1; SMN2PKM | |
| SCHEMBL14712812 | 0.72 | LTA4H (0.47) | MMP2MMP9MMP12MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166127-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4101667-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |