Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.42 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29143247 | 0.89 | SIRT1 (0.47) | ALDH1A1GLAL3MBTL1MAPK1CYP2C9 | |
| SCHEMBL11442736 | 0.84 | SLC6A9 (0.45) | ALDH1A1GLAL3MBTL1MAPK1CYP2C9 | |
| SCHEMBL11552435 | 0.84 | SLC6A2 (0.44) | ALDH1A1CYP2C9CYP2C19HPGDMMP2 | |
| Oxirane SCHEMBL11442758 | 0.82 | SIRT1 (0.41) | ALDH1A1GLAL3MBTL1MAPK1CYP2C9 | |
| SCHEMBL11430852 | 0.81 | MMP2 (0.60) | ALDH1A1SLC6A9MMP2MMP9MMP12 | |
| SCHEMBL11554666 | 0.79 | MMP2 (0.49) | ALDH1A1CYP2C9CYP2C19HPGDMMP2 | |
| SCHEMBL11400372 | 0.77 | MMP2 (0.38) | ALDH1A1L3MBTL1CYP2C9CYP2C19HPGD | |
| SCHEMBL10482126 | 0.72 | SIRT1 (0.56) | ALDH1A1GLAL3MBTL1MAPK1CYP2C9 | |
| SCHEMBL3640100 | 0.72 | CYP2C9 (0.72) | ALDH1A1GLAL3MBTL1MAPK1CYP2C9 | |
| SCHEMBL30548760 | 0.72 | HTR1A (0.51) | ALDH1A1GLAL3MBTL1MAPK1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228284-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4166127-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4101667-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |