Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29143247 | 0.85 | SIRT1 (0.47) | MAPTKDM4EALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL11427398 | 0.84 | ALDH1A1 (0.46) | MAPTKDM4EALDH1A1HTR1AHTR3A | |
| Oxirane SCHEMBL11442758 | 0.78 | SIRT1 (0.41) | MAPTKDM4EALDH1A1CYP2C9HPGD | |
| SCHEMBL11430852 | 0.78 | MMP2 (0.60) | ALDH1A1HTR1AHTR3AMMP2MMP9 | |
| SCHEMBL11554666 | 0.76 | MMP2 (0.49) | MAPTKDM4EALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL11442736 | 0.75 | SLC6A9 (0.45) | ALDH1A1CYP2C9HPGDCYP2C19PPARG | |
| SCHEMBL11400372 | 0.74 | MMP2 (0.38) | ALDH1A1CYP2C9HPGDCYP2C19MMP2 | |
| SCHEMBL8529802 | 0.74 | SLC6A2 (0.48) | SLC6A2SLC6A4SLC6A3MAPTKDM4E | |
| SCHEMBL28437694 | 0.71 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3MAPTKDM4E | |
| SCHEMBL27985674 | 0.71 | ACP3 (0.50) | ALDH1A1HPGDPPARGPPARAACP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166127-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4101667-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |