Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558455 | 0.87 | RIPK1 (0.37) | RIPK1KDM4ERORCCYP2D6OPRK1 | |
| SCHEMBL11556325 | 0.85 | TSHR (0.42) | LMNAL3MBTL1NPSR1ALDH1A1HSD17B10 | |
| SCHEMBL11557137 | 0.84 | ALOX15 (0.46) | LMNATHRBNPSR1ALDH1A1POLB | |
| SCHEMBL11561701 | 0.84 | MCL1 (0.36) | LMNANPSR1ALDH1A1POLBHSD17B10 | |
| SCHEMBL11555657 | 0.82 | P2RX7 (0.38) | ALDH1A1TRPV1RORC | |
| SCHEMBL11564389 | 0.82 | AKR1B1 (0.36) | L3MBTL1ALDH1A1POLBKDM4EHSD17B10 | |
| SCHEMBL11076395 | 0.67 | CYP1A2 (0.48) | LMNARIPK1CYP1A2CYP2C19NPSR1 | |
| SCHEMBL11560739 | 0.63 | NQO2 (0.40) | THRBCYP1A2CYP2C19NPSR1ALDH1A1 | |
| SCHEMBL6307140 | 0.63 | ITGB3 (0.66) | CYP1A2CYP2C19NPSR1MAPTCYP2D6 | |
| SCHEMBL6345014 | 0.63 | ITGB3 (0.66) | CYP1A2CYP2C19NPSR1MAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |