Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558080 | 0.85 | MAPT (0.36) | PTGS2PTGS1BRD4CREBBP | |
| SCHEMBL11556858 | 0.84 | BRD4 (0.38) | BRD4CREBBPNR3C2 | |
| SCHEMBL11557429 | 0.84 | MMP12 (0.38) | BRD4CREBBP | |
| SCHEMBL11558077 | 0.83 | ATAD2 (0.38) | CA9 | |
| SCHEMBL11558220 | 0.83 | KCNE1 (0.34) | AKR1B1NR3C2PSEN1PSEN2APH1B | |
| SCHEMBL11560192 | 0.83 | LMNA (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11559426 | 0.80 | TRPV1 (0.35) | KCNH2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL11560034 | 0.80 | SMN1; SMN2 (0.37) | L3MBTL1MAPK1CA12CA1CA9 | |
| SCHEMBL11560946 | 0.80 | ALPL (0.34) | BRD4CREBBP | |
| SCHEMBL11560739 | 0.78 | NQO2 (0.40) | BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |