Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 5/20 | 0.33 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557429 | 0.87 | MMP12 (0.38) | LMNATP53HTT | |
| SCHEMBL11558220 | 0.86 | KCNE1 (0.34) | PGRKCNE1KCNQ1PSEN1PSEN2 | |
| SCHEMBL11558080 | 0.86 | MAPT (0.36) | LMNASMN1; SMN2ABCC9 | |
| SCHEMBL11558077 | 0.86 | ATAD2 (0.38) | SMN1; SMN2 | |
| SCHEMBL11559728 | 0.84 | GAA (0.37) | NPSR1SMN1; SMN2PGR | |
| SCHEMBL11565708 | 0.83 | PTGS2 (0.34) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11559426 | 0.83 | TRPV1 (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL11560034 | 0.83 | SMN1; SMN2 (0.37) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL11560946 | 0.83 | ALPL (0.34) | LMNANPSR1SMN1; SMN2PARP1 | |
| SCHEMBL11556858 | 0.80 | BRD4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |