Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11560097 | 0.82 | SMN1; SMN2 (0.45) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL11562101 | 0.80 | RAB9A (0.46) | NPC1RAB9AHTT | |
| SCHEMBL11565091 | 0.74 | NPC1 (0.51) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL11565089 | 0.74 | NPC1 (0.51) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL11565008 | 0.71 | SMN1; SMN2 (0.47) | NPC1RAB9AALDH1A1KMT2ATDP1 | |
| SCHEMBL23147211 | 0.69 | PTGS2 (0.45) | KDM4EKMT2ALMNA | |
| Ammonia Solution, Strong SCHEMBL11559116 | 0.68 | RAB9A (0.47) | NPC1RAB9AKDM4EKMT2AMAPT | |
| SCHEMBL21978654 | 0.66 | MAPT (0.63) | NPC1RAB9AALDH1A1KMT2AMAPT | |
| SCHEMBL11560398 | 0.66 | MEN1 (0.51) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL2048930 | 0.64 | ALDH1A1 (0.57) | RAB9AALDH1A1KDM4EKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147528-A | 6-Oxopyrimidine plant growth regulators | ROHM AND HAAS COMPANY (US) | 1979-04-03 | — | — | US | disclosed |