SCHEMBL1159910

SCHEMBL1159910

c1ccc2c3c(ccc2c1)CNN3

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
HSD17B10 Q99714 3/20 0.42
CYP2A6 P11509 3/20 0.42
TSHR P16473 2/20 0.42
TDP1 Q9NUW8 1/20 0.42
HPRT1 P00492 1/20 0.39
HIF1A Q16665 1/20 0.37
CYP1B1 Q16678 1/20 0.37
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34
CYP1A2 P05177 2/20 0.33
PTPN22 Q9Y2R2 1/20 0.33
KIF11 P52732 1/20 0.33
PAX8 Q06710 1/20 0.33
ANPEP P15144 1/20 0.33
HPGD P15428 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12799615 0.81 HSD17B10 (0.39) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL4421747 0.79 ALDH1A1 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL28889640 0.73 HSD17B10 (0.39) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL9707362 0.71 HPRT1 (0.54) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL1287806 0.71 CA12 (0.47) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL1159909 0.69 HSD17B10 (0.44) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL634543 0.68 HSD17B10 (0.42) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL31668742 0.68 HSD17B10 (0.42) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL4298702 0.67 HSD17B10 (0.46) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL31301198 0.67 ALDH1A1 (0.41) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US claimed
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 EP claimed
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME INFINEUM INTERNATIONAL LIMITED (GB) 2024-08-29 US claimed
EP-4410772-A2 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME Infineum International Limited (GB) 2024-08-07 EP claimed
CN-118440229-A Amine functional monomers and methods of making the same 英菲诺姆国际有限公司 2024-08-06 CN claimed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 WO claimed
CN-109503487-B Dihydrobenzandazole compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2020-12-22 CN claimed
CN-109678799-B Dihydrobenzandazole compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2020-12-22 CN claimed
CN-109535130-B Dihydrobenzandazole compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2020-12-22 CN claimed
CN-109721540-A Dihydrobenzo indazole compounds, organic electroluminescence device and display device 阜阳欣奕华材料科技有限公司 2019-05-07 CN claimed
CN-109207145-A A kind of organic electroluminescence device and display 李现伟 2019-01-15 CN claimed
CN-109206414-A Dihydrobenzo indazole class electroluminescent organic material 李现伟 2019-01-15 CN claimed
CN-109206369-A A kind of dihydrobenzo indazole class electroluminescent organic material 李现伟 2019-01-15 CN claimed
CN-109206368-A A kind of dihydrobenzo indazole class electroluminescent organic material 李现伟 2019-01-15 CN claimed
CN-109206412-A A kind of organic electroluminescence device and display 李现伟 2019-01-15 CN claimed
CN-109206404-A A kind of dihydrobenzo indazole class electroluminescent organic material 李现伟 2019-01-15 CN claimed
EP-2459551-B1 DIHYDROBENZOINDAZOLES MERCK SHARP & DOHME (NL) 2014-07-02 EP claimed
EP-2459551-A1 DIHYDROBENZOINDAZOLES MSD Oss B.V. (NL) 2012-06-06 EP claimed
WO-2011012674-A1 DIHYDROBENZOINDAZOLES N.V. ORGANON (NL) 2011-02-03 WO claimed
US-20110028451-A1 Dihydrobenzoindazoles N.V. ORGANON (NL) 2011-02-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME AMD1, HNMT, MAT1A ALDH1A1 317/4885HSD17B10 2763/4885CYP2A6 4391/4885
US-20110028451-A1 Dihydrobenzoindazoles DHODH, BRDT, HSD17B11 ALDH1A1 54/4885HSD17B10 139/4885CYP2A6 786/4885
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF FSHR, GNRHR, LHCGR ALDH1A1 3439/4885HSD17B10 568/4885CYP2A6 3436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.