SCHEMBL1159909

SCHEMBL1159909

c1ccc2c3c(ccc2c1)NNC3

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.44
ALDH1A1 P00352 3/20 0.44
CYP2A6 P11509 2/20 0.44
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
HPRT1 P00492 1/20 0.41
LMNA P02545 1/20 0.39
HIF1A Q16665 1/20 0.38
CYP1B1 Q16678 1/20 0.38
KDM4E B2RXH2 3/20 0.37
CYP1A2 P05177 3/20 0.37
HPGD P15428 2/20 0.37
CYP2C19 P33261 2/20 0.37
GLA P06280 1/20 0.37
CYP2C9 P11712 1/20 0.37
SIRT1 Q96EB6 1/20 0.37
HTT P42858 1/20 0.37
CDK5 Q00535 1/20 0.37
CDK5R1 Q15078 1/20 0.37
NCOA1 Q15788 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31712962 0.88 HSD17B10 (0.41) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL31712977 0.86 ALDH1A1 (0.39) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL123642 0.84 HSD17B10 (0.41) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL845562 0.82 ALDH1A1 (0.39) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL7856090 0.80 ALDH1A1 (0.37) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL31712991 0.77 HSD17B10 (0.38) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL28762990 0.73 IMPDH2 (0.40) LMNAKDM4ECYP1A2CYP2C19CYP2C9
SCHEMBL25366218 0.72 LMNA (0.44) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL31712961 0.69 KDM4E (0.44) HSD17B10ALDH1A1CYP2A6TSHRTDP1
SCHEMBL1159910 0.69 ALDH1A1 (0.42) HSD17B10ALDH1A1CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US claimed
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 EP claimed
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME INFINEUM INTERNATIONAL LIMITED (GB) 2024-08-29 US claimed
EP-4410772-A2 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME Infineum International Limited (GB) 2024-08-07 EP claimed
CN-118440229-A Amine functional monomers and methods of making the same 英菲诺姆国际有限公司 2024-08-06 CN claimed
WO-2024077006-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY, INC. (US) 2024-04-11 WO claimed
CN-109503487-B Dihydrobenzandazole compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2020-12-22 CN claimed
CN-109678799-B Dihydrobenzandazole compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2020-12-22 CN claimed
CN-109535130-B Dihydrobenzandazole compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2020-12-22 CN claimed
EP-2459551-B1 DIHYDROBENZOINDAZOLES MERCK SHARP & DOHME (NL) 2014-07-02 EP claimed
EP-2459551-A1 DIHYDROBENZOINDAZOLES MSD Oss B.V. (NL) 2012-06-06 EP claimed
WO-2011012674-A1 DIHYDROBENZOINDAZOLES N.V. ORGANON (NL) 2011-02-03 WO claimed
US-20110028451-A1 Dihydrobenzoindazoles N.V. ORGANON (NL) 2011-02-03 US claimed
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF RADIONETICS ONCOLOGY INC (US) 2026-05-21 US disclosed
EP-4598928-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF Radionetics Oncology, Inc. (US) 2025-08-13 EP disclosed
CN-113328042-B Organic electroluminescent element and preparation method thereof 固安鼎材科技有限公司 2025-03-25 CN disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287009-A1 AMINE-FUNCTIONAL MONOMERS AND METHODS OF MAKING SAME AMD1, HNMT, MAT1A HSD17B10 2763/4885ALDH1A1 317/4885CYP2A6 4391/4885
US-20110028451-A1 Dihydrobenzoindazoles DHODH, BRDT, HSD17B11 HSD17B10 139/4885ALDH1A1 54/4885CYP2A6 786/4885
US-20260137819-A1 FOLLICLE-STIMULATING HORMONE RECEPTOR (FSHR) TARGETED THERAPEUTICS AND USES THEREOF FSHR, GNRHR, LHCGR HSD17B10 568/4885ALDH1A1 3439/4885CYP2A6 3436/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.