Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.34 |
| ▸ | CCR2 | P41597 | 4/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.32 |
| ▸ | MGLL | Q99685 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615779 | 0.83 | KDM4E (0.45) | PKMKDM4EPOLBABCB11GPR35 | |
| SCHEMBL11616083 | 0.82 | POLB (0.43) | PKMKDM4EPOLBMAPTCCR2 | |
| SCHEMBL11618317 | 0.80 | POLB (0.49) | PKMKDM4EPOLBMAPTABCB11 | |
| SCHEMBL11613152 | 0.78 | FABP4 (0.47) | PKMKDM4EPOLBABCB11 | |
| SCHEMBL11621960 | 0.78 | POLB (0.42) | PKMKDM4EPOLBABCB11GPR35 | |
| SCHEMBL11613651 | 0.77 | KDM4E (0.46) | PKMKDM4EPOLBABCB11GPR35 | |
| SCHEMBL11613646 | 0.77 | KDM4E (0.46) | PKMKDM4EPOLBABCB11GPR35 | |
| SCHEMBL11617064 | 0.75 | GPR35 (0.49) | PKMKDM4EPOLBMAPTGPR35 | |
| SCHEMBL7425362 | 0.69 | CCR2 (0.63) | POLBGPR35CCR2MEN1KMT2A | |
| SCHEMBL9613230 | 0.69 | GPR35 (0.48) | POLBABCB11GPR35CCR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4130649-A | Cyclohepta [B]pyridine-2-carboxylic acid derivatives | AYERST, MCKENNA & HARRISON LIMITED (CA) | 1978-12-19 | — | — | US | disclosed |